A0A4R6UXI8 · A0A4R6UXI8_9ACTN
- ProteinTranslation initiation factor IF-2
- GeneinfB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids613 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | translation initiation factor activity |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameTranslation initiation factor IF-2
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Streptosporangiales > Nocardiopsaceae > Actinorugispora
Accessions
- Primary accessionA0A4R6UXI8
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 106-278 | Tr-type G | ||||
Sequence: ARPPVVTVMGHVDHGKTRLLDAIRNTNVVSGEAGGITQHIGAYQVATEVDGEERRITFIDTPGHEAFTAMRARGAQATDIAVLVVAADDGVKPQTAEAIDHAKAAEVPIVVAVNKIDVEGADPQRVRAQLTEYGLVAEEYGGDVQFVDISAKQGVNIDGLLEAVVLTSDASLD |
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length613
- Mass (Da)66,403
- Last updated2019-07-31 v1
- Checksum176C4D5319C83B68
Keywords
- Technical term