A0A4D7D8S4 · A0A4D7D8S4_9SPHN

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site108-111substrate
Active site110Proton acceptor
Binding site130K+ (UniProtKB | ChEBI)
Binding site133ATP (UniProtKB | ChEBI)
Binding site188substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      FA702_05135

Organism names

  • Taxonomic identifier
  • Strain
    • ABRDHK2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Novosphingobium

Accessions

  • Primary accession
    A0A4D7D8S4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    259
  • Mass (Da)
    27,941
  • Last updated
    2019-07-31 v1
  • Checksum
    B0A7A983DF117FDD
MLLAIDVGNTNVVFALYAGRTIKSRWRVATDPRRTADEYAVWLLQLMQLQGFAADDVDQIIVSTVVPRALHNLQVLAQKYFHRDALIAGQPPIEWGIDIDVDEPRSLGADRAVNAIAAHANYPGDLIVVDFGTATTFDVVDFNGAYKGGIIAPGINLSLEALVNAAAKLPRIAIAPPSRTNSVIGRNTEDQMQIGVFWGYVSLMEGLIARMRAEVGRPAKVIATGGLAVLFGDHTTIFDHVDTDLTLDGLAILAERAPS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP039695
EMBL· GenBank· DDBJ
QCI92995.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp