A0A3R9T657 · A0A3R9T657_ACIBA

  • Protein
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  • Gene
    murF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site121-127ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Molecular FunctionUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  • EC number
  • Alternative names
    • D-alanyl-D-alanine-adding enzyme

Gene names

    • Name
      murF
    • ORF names
      EA706_01690
      , P9867_017320
      , P9867_05015

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • TG22168
    • CPO519
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    A0A3R9T657

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain36-87Mur ligase N-terminal catalytic
Domain120-303Mur ligase central
Domain326-436Mur ligase C-terminal

Sequence similarities

Belongs to the MurCDEF family. MurF subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    466
  • Mass (Da)
    50,725
  • Last updated
    2019-04-10 v1
  • Checksum
    748416CEEFEA902E
MHTSTTSTVPLEPWTAQQLQQATQGYWHKDQIPQSEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVAANGCQVAIVERPIDAEIAQLVVADTRLALGQLGAYRREQNAQLKVIALTGSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLGVPMMLLELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICRAKSEIYRHILPQGVAIVPQQDDFTAEIREAAKSHQIMSFGAGGDVFATEIELLPQSANFQLHTPQGSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQKAPHLFIDDTYNANPTSMRAAAQVLLQQNGIKVMVMGDIGELGDSSWQEHHDLGRDLAELPLDHIVAVGQFASAALEGAGLHSTKLKAFQTQAEALPFLINLIQTHQPQSMSFLFKGSRFTHMETLMADLMEKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JARTMM010000012
EMBL· GenBank· DDBJ
MDK4881092.1
EMBL· GenBank· DDBJ
Genomic DNA
JARTMM020000001
EMBL· GenBank· DDBJ
MEC5498149.1
EMBL· GenBank· DDBJ
Genomic DNA
RFCO01000004
EMBL· GenBank· DDBJ
RSQ49451.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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