A0A3Q9FFA2 · A0A3Q9FFA2_9ASCO

  • Protein
    polynucleotide adenylyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions. Also active with manganese.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

155450100150200250300350400450500550
TypeIDPosition(s)Description
Binding site86-88ATP (UniProtKB | ChEBI)
Binding site99Mg2+ 1 (UniProtKB | ChEBI); catalytic
Binding site99Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site99-101ATP (UniProtKB | ChEBI)
Binding site101Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site101Mg2+ 1 (UniProtKB | ChEBI); catalytic
Binding site153ATP (UniProtKB | ChEBI)
Binding site153Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site214ATP (UniProtKB | ChEBI)
Binding site223ATP (UniProtKB | ChEBI)
Binding site232-233ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpoly(A) RNA polymerase activity
Molecular FunctionRNA binding
Biological ProcessmRNA processing
Biological ProcessRNA 3'-end processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    polynucleotide adenylyltransferase
  • EC number

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NRRL Y-27587
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Debaryomycetaceae > Suhomyces

Accessions

  • Primary accession
    A0A3Q9FFA2

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-20Disordered
Domain7-200Poly(A) polymerase nucleotidyltransferase
Domain205-349Poly(A) polymerase central
Domain352-527Poly(A) polymerase RNA-binding
Region522-554Disordered

Sequence similarities

Belongs to the poly(A) polymerase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    554
  • Mass (Da)
    62,794
  • Last updated
    2019-04-10 v1
  • Checksum
    1153E750356B8349
MSGQTYGVTPPISVANPTPKENEFNDTLITELKTRGSFESEAATRKRVEVLSILQKLTEEFVYTVSLKRNMSEGMARDAGGKIFTFGSYRLGVYGPGSDIDTLVLVPRHVTRNDFFEVFTELLRKQPEVDEIAPVPDAFVPVIELVFSGIAIDLLCAKLDIPRIPKDLTLDDKNLLRNIDEKDLRALNGTRVTDEILQLVPKPTVFKHALRCIKMWAQNRAVYANIFGFPGGVAWAMLVARICQLYPNAVSAVIVEKFFNIYSQWSWPQPVLLKQIEDGPLQIRVWNPRLYPHDRQHKMPVITPAYPSMCATHNISSSTQKVILDEFNRGVTIMQGIVGGSKSWSDLLQRHDFFHKYKFYLCIVAGTQSTHEQHLQFSGLVESKLRLLVQKLEAVEGIELAHPYVKSFDNGYFAESDTQLQNIVNTYGTLEGEDVTKDVKTTEDEAKEELAKDHLELHLTKLYIGLKIDLQKGDKKLDIQYPCSEFFGICKSWQHFDSKIHHIQIKNVKLYDLPNDVYVEGEVRPSKPTKRKRAGSKNEIQKRPKSVGPVSASS

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH707262
EMBL· GenBank· DDBJ
AZQ56618.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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