A0A3Q8I2V0 · A0A3Q8I2V0_MUSSP

Function

function

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Features

Showing features for binding site.

140050100150200250300350400
TypeIDPosition(s)Description
Binding site345Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionarachidonic acid epoxygenase activity
Molecular Functionaromatase activity
Molecular Functionheme binding
Molecular Functioniron ion binding
Biological Processepoxygenase P450 pathway
Biological Processxenobiotic metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome P450
  • EC number

Gene names

    • Name
      Cyp2b10

Organism names

Accessions

  • Primary accession
    A0A3Q8I2V0

Subcellular Location

Endoplasmic reticulum membrane
; Peripheral membrane protein
Microsome membrane
; Peripheral membrane protein

Keywords

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    400
  • Mass (Da)
    45,895
  • Last updated
    2019-04-10 v1
  • Checksum
    949D6CFC9BD508E5
AEAFSGRGTIAVVEPTFKEYGVIFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLKYFPGAHRQISKNLQELLDYIGHSVEKHRATLDPSVPRDFIDIYLLRMEKEKSNQHTEFHHQNLMMSVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLIPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANGALKKSEAFLPFSTGKRICLGEGIARNELFLFFTSILQNFSVSSPVAPKDIDLTPKESGVGKIPPTYQICFLAR

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue400

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MF947508
EMBL· GenBank· DDBJ
AYK27082.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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