A0A3Q8I2V0 · A0A3Q8I2V0_MUSSP
- ProteinCytochrome P450
- GeneCyp2b10
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids400 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Catalytic activity
- an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H+
Cofactor
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | arachidonic acid epoxygenase activity | |
Molecular Function | aromatase activity | |
Molecular Function | heme binding | |
Molecular Function | iron ion binding | |
Biological Process | epoxygenase P450 pathway | |
Biological Process | xenobiotic metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytochrome P450
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A3Q8I2V0
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Peripheral membrane protein
Microsome membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Sequence
- Sequence statusFragment
- Length400
- Mass (Da)45,895
- Last updated2019-04-10 v1
- Checksum949D6CFC9BD508E5
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: A | ||||||
Non-terminal residue | 400 | |||||
Sequence: R |