A0A3Q3F0P5 · A0A3Q3F0P5_KRYMA

Function

function

Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site210Fe (UniProtKB | ChEBI) of heme 2 (UniProtKB | ChEBI); axial binding residue
Binding site254Fe (UniProtKB | ChEBI) of heme 2 (UniProtKB | ChEBI); axial binding residue

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcollagen-containing extracellular matrix
Cellular Componentextracellular space
Molecular Functionheme transmembrane transporter activity
Molecular Functionmetal ion binding
Biological Processintracellular iron ion homeostasis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Hemopexin

Organism names

Accessions

  • Primary accession
    A0A3Q3F0P5

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond18↔205
Disulfide bond123↔128
Disulfide bond162↔174
Disulfide bond322↔364

Keywords

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat61-113Hemopexin
Repeat114-158Hemopexin
Repeat159-205Hemopexin
Repeat221-265Hemopexin
Repeat266-313Hemopexin

Sequence similarities

Belongs to the hemopexin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    407
  • Mass (Da)
    46,116
  • Last updated
    2019-04-10 v1
  • Checksum
    533A6213B7361EAC
FCIFFVCFCRYAAVPDRCTGIEFDAITPDDKGNALFFKDGHIWKGFHGPAQLSSEHFKELTGHVDAAFRMHNTGNPDDHDHIYLFMGDKVFSYFNQSLEEGYPKQIQEDFPGVPAHLDAAVECPKGECIADSVLFFKGQDVYVYDITTKTVKTKAWSHLPSCTSIFRWLEHYYCFHGHNFTRFHPVTGEVVGEYPKDTRNYFMRCPNFGHGSNHKPVKCSEVKLDAATTDDTGRTYFFSGSSYMRQDTHRDGFHNFPIIRGWKEVTNGVDAVFSYTNKIYLIKGDQIYIYKADAHFTLIEGYPKTVKEELGIEGHVDAAFVCPTENVAHIFQGNRMRDVDLTATPRIIVQDRPLPLSDIDAGLCGADGIKLFKGSQYYSYESPMILAMGRIAPRPAHITSAMMACED

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3Q3F0S4A0A3Q3F0S4_KRYMA407

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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