A0A3P9CL58 · A0A3P9CL58_9CICH

Function

function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentconnexin complex
Molecular Functiongap junction channel activity
Biological Processcell-cell signaling

Subcellular Location

Cell junction, gap junction
Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-41Helical
Transmembrane78-100Helical
Transmembrane210-228Helical

Keywords

Interaction

Subunit

A connexon is composed of a hexamer of connexins.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, coiled coil, compositional bias, region.

TypeIDPosition(s)Description
Domain43-76Connexin N-terminal
Coiled coil100-141
Domain167-233Gap junction protein cysteine-rich
Compositional bias399-428Polar residues
Region399-447Disordered

Sequence similarities

Belongs to the connexin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    456
  • Mass (Da)
    51,546
  • Last updated
    2019-02-13 v1
  • Checksum
    0C1A0CCD52C60F8F
MGDWNLLGSILEEVHIHSTIVGKIWLTILFIFRMLILGAAAEDVWDDEQSEFVCNTDQPGCKAVCYDRAFPISLIRFWVLQVIFVSAPSLVYMGHALYCIRSLEKERHRRRAQLKEELDEAELALDEQKRVERELRRLEEQRKVKKAPLRGSLLRTYIIHILTRSVVEICFILGQYILYGVQLEPLYKCERLPCPNSVDCYISRPTEKTIFMAFMIAIAGVSLFLNILEISHLGIRKIKQVLYAERYTEDDSLIYKSKRKSSLPHLCVTSNVSPHDGPLTQTFKVIPGADLKPSHYNTRNPPTSALSCAIQAPQTSEGSEVPTNLDLSQAWIPVMSTADGTQTSHKDIHEEDHPHPSHLEALLASSNVRPRAIPNLNENERRESVGSEFLIPNTRKTSFMIRPPSESLSSMTGSTSPSLHTSEESDELGSLQGDMPMMPPAGGRRMSMASKHILWK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias399-428Polar residues

Keywords

Genome annotation databases

Similar Proteins

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