A0A3P9C7U2 · A0A3P9C7U2_9CICH

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site, site.

141350100150200250300350400
TypeIDPosition(s)Description
Binding site225-230strychnine (UniProtKB | ChEBI)
Site284Important for obstruction of the ion pore in the closed conformation

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloride channel complex
Cellular Componentneuron projection
Cellular Componentplasma membrane
Cellular Componentpostsynapse
Molecular Functionchloride channel activity
Molecular Functionexcitatory extracellular ligand-gated monoatomic ion channel activity
Molecular Functionglycine binding
Molecular Functiontransmembrane signaling receptor activity
Molecular Functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Glycine receptor subunit alphaZ1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Cichlomorphae > Cichliformes > Cichlidae > African cichlids > Pseudocrenilabrinae > Haplochromini > Maylandia > Maylandia zebra complex

Accessions

  • Primary accession
    A0A3P9C7U2

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein
Synapse

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane245-267Helical
Transmembrane308-331Helical
Transmembrane385-405Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_502226730724-413
Disulfide bond161↔175
Disulfide bond221↔232

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain38-243Neurotransmitter-gated ion-channel ligand-binding
Domain250-336Neurotransmitter-gated ion-channel transmembrane

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    413
  • Mass (Da)
    47,799
  • Last updated
    2019-02-13 v1
  • Checksum
    193E0E38BB9F9129
VILFSTLIYIFIFILFFPELDHAVRTRQVPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQENGPVQVADGLTLPQFILKDESDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRHNKNKSKNATQNAPAAASGGKSMEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRHEDVHKQ

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3P9C7A3A0A3P9C7A3_9CICH510
A0A3P9C7W4A0A3P9C7W4_9CICH467

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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