A0A396S4A7 · A0A396S4A7_9SPHN

  • Protein
    Aconitate hydratase
  • Gene
    acnA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
Organic acid metabolism; propanoate degradation.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function2-methylisocitrate dehydratase activity
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionaconitate hydratase activity
Molecular Functioniron-responsive element binding
Molecular Functionmetal ion binding
Biological Processcitrate metabolic process
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aconitate hydratase
  • EC number
  • Short names
    Aconitase

Gene names

    • Name
      acnA
    • ORF names
      D1610_07210

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ZDH117
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingomonas

Accessions

  • Primary accession
    A0A396S4A7

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain71-561Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Domain691-816Aconitase A/isopropylmalate dehydratase small subunit swivel

Sequence similarities

Belongs to the aconitase/IPM isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    889
  • Mass (Da)
    95,708
  • Last updated
    2018-12-05 v1
  • Checksum
    92398646A464B828
MTALGQDSLGTRSTLSVGGKSLDYFSIEKAAAKLGDVSRLPFSMKVLLENLLRFEDGETVTETDIQAIIDWQQERRSDREIQYRPARVLMQDFTGVPCVVDLAAMRDAITSLGGDAAKINPQVPVHLVIDHSVMVDEFGTPRAFEDNVELEYQRNGERYEFLKWGSKALDNFKVVPPGTGICHQVNLENIAQSVWTSTAADGATIAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPEVVGFKLTGALAEGITATDLVLTVTQMLRAKGVVGRFVEFYGPGMAALSLADRATIANMAPEYGATCGFFPVDAKTIDYMRLTGRDEETLALVEAYCKAQGLWADPNVEPVFTDTLKLDMSSVQPSLAGPKRPQDKVSLSKVDEVFNGDLTKLYKKEAPARVPVSGREHDIGDGDVVIAAITSCTNTSNPSVLIAAGLVARKAVALGLKPKPWVKTSLAPGSQVVTDYLDKAGLTADLNAIGFNLVGYGCTTCIGNSGPLAEPISNAINGNDIVAASVLSGNRNFEGRVSADVRANFLASPPLVVAYALKGTVTEDMIETPIGQSTEGADVYLKDIWPSNDEVRALIDANIDSGMFRARYADVYNGDDKWRAIDVAGSDTYTWRAGSTYIANPPYFEGMTMTPAPVRDIIEAKPLAILGDSITTDHISPAGSIKADSPAGTFLQEHQVSRADFNSYGARRGNHNVMMRGTFANIRIKNEMVPGVEGGMTSYKGETMPIYDAAMRHKADGTPLIVIAGKEYGTGSSRDWAAKGTNLLGVRAVITESFERIHRSNLVGMGVLPLQFADGVTRETLKLDGSETFTIMKVAEIRPRQDVEVTLTRADGTVETFQTKCRIDTVNELEYFLNGGILQYVLRKLAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QWLV01000002
EMBL· GenBank· DDBJ
RHW18255.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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