A0A383ZZJ7 · A0A383ZZJ7_BALAS
- ProteinN(6)-L-threonylcarbamoyladenine synthase
- GeneOSGEP
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids335 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- L-threonylcarbamoyladenylate + adenosine37 in tRNA = N6-L-threonylcarbamoyladenosine37 in tRNA + AMP + H+
Cofactor
Note: Binds 1 divalent metal cation per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 109 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 113 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 130 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 130-134 | substrate | ||||
Sequence: YVSGG | ||||||
Binding site | 162 | substrate | ||||
Sequence: D | ||||||
Binding site | 177 | substrate | ||||
Sequence: G | ||||||
Binding site | 181 | substrate | ||||
Sequence: E | ||||||
Binding site | 266 | substrate | ||||
Sequence: N | ||||||
Binding site | 294 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | EKC/KEOPS complex | |
Cellular Component | nucleus | |
Molecular Function | metal ion binding | |
Molecular Function | N(6)-L-threonylcarbamoyladenine synthase activity | |
Biological Process | tRNA threonylcarbamoyladenosine modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameN(6)-L-threonylcarbamoyladenine synthase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Whippomorpha > Cetacea > Mysticeti > Balaenopteridae > Balaenoptera
Accessions
- Primary accessionA0A383ZZJ7
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 29-300 | Gcp-like | ||||
Sequence: RRTYVTPPGTGFLPGATARHHRTVILDLLQEALTEAGLTSKDIDCIAYTKGPGMGAPLVSAAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGATSPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPYTVKGMDVSFSGILSFIEDVTQRMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSQEALIVGGVGCNMRLQEMMETMCQERGAQLFATDERFCIDNGAMIA |
Sequence similarities
Belongs to the KAE1 / TsaD family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length335
- Mass (Da)36,451
- Last updated2018-11-07 v1
- Checksum0ADA2E7265A15182
Keywords
- Technical term