A0A354IGN3 · A0A354IGN3_9FIRM
- ProteinBifunctional chorismate mutase/prephenate dehydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids380 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
Catalytic activity
- H+ + prephenate = 3-phenylpyruvate + CO2 + H2O
Pathway
Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.
Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 276 | Essential for prephenate dehydratase activity | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | chorismate mutase activity | |
Molecular Function | prephenate dehydratase activity | |
Biological Process | chorismate metabolic process | |
Biological Process | L-phenylalanine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional chorismate mutase/prephenate dehydratase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales
Accessions
- Primary accessionA0A354IGN3
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-83 | Chorismate mutase | ||||
Sequence: MRNIEEIRRDISAIDHQILELFLKRMRCAEEVSDYKMANGGQVLVPSRETELLSTMLKDIPDDLKLEYTALLRTTTRVSRKHQ | ||||||
Domain | 108-283 | Prephenate dehydratase | ||||
Sequence: TVYYGGLPASYADMACAALFPNADRCAKNSWEEVFLAVLNGEAEVGVVPVENSTAGTVNEVYDLLEQYGLYISRSYISAIRHCIAGCKGTSLDTIKEVHSHPQALRQCQQYIKTHGFAPVEESNTAVAARDVAQQGDPTQAAICSEAAARLYGLEILQTQVNDGDFNQTRFIAVTR | ||||||
Domain | 295-372 | ACT | ||||
Sequence: SVVITLPHVAGSLYGALAVFADHGVNMTEIHSRPLRDMPWNYCFYIDFEGNLLEPNTCALIYQLTQECAHIRVLGSYP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length380
- Mass (Da)42,498
- Last updated2018-11-07 v1
- ChecksumCBD4D825FC9EDAC1