A0A2Z6B1L3 · A0A2Z6B1L3_9BACT

Function

function

Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site230L-serine (UniProtKB | ChEBI)
Binding site230-232L-serine (UniProtKB | ChEBI)
Binding site261L-serine (UniProtKB | ChEBI)
Binding site261-263ATP (UniProtKB | ChEBI)
Binding site284L-serine (UniProtKB | ChEBI)
Binding site348-351ATP (UniProtKB | ChEBI)
Binding site382L-serine (UniProtKB | ChEBI)
Binding site384L-serine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionserine-tRNA ligase activity
Biological Processselenocysteine biosynthetic process
Biological Processseryl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine--tRNA ligase
  • EC number
  • Alternative names
    • Seryl-tRNA synthetase
      (SerRS
      )
    • Seryl-tRNA(Ser/Sec) synthetase

Gene names

    • Name
      serS
    • ORF names
      DFE_2560

Organism names

  • Taxonomic identifier
  • Strain
    • IS5
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Desulfovibrio

Accessions

  • Primary accession
    A0A2Z6B1L3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer. The tRNA molecule binds across the dimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain171-409Aminoacyl-transfer RNA synthetases class-II family profile

Domain

Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    425
  • Mass (Da)
    48,006
  • Last updated
    2018-10-10 v1
  • Checksum
    8D6EB9370E44CC3F
MLDLKFIRKNLDVVRESVARRRAKVDVDAFTGLDERRRALIAEAEVLKAERNTVSKDIGKRKKAGEDAADLVSRMGEVGDRIKSLDEELRQVDAEVRDWLESVPNIPHESVVDGNDDADNPEVFRWGAKPEFDFTPKEHYELGANLDGLDFERGAKLAGSRFVVYRGWAARLERALASFMLDVQTLEHGYKEIMPPVIVNTETMTATGQLPKFAEDLFKLEGTDYYLIPTAEVPVTNLHREETIAEDELPLKYTAWTPCFRSEAGSYGKDTKGLIRMHQFQKVEMVRFEKPEDSFAALEEMREHAENILKKLGLHYRVVTLCTGDLGFSATKTYDLEVWLPGQDKFREISSCSNCMDFQARRGGIRFKRKGAKKAELVHTLNGSGLAVGRTLVAVLENYQQADGSIVIPEVLRPYMGGLEVLKSE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP017378
EMBL· GenBank· DDBJ
BBD09286.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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