A0A2Z3XCX8 · A0A2Z3XCX8_9ENTR

Function

function

Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 manganese ions per subunit.

Pathway

Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (hydrolase route): step 1/1.

Features

Showing features for binding site.

131320406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site130Mn2+ 1 (UniProtKB | ChEBI)
Binding site155Mn2+ 2 (UniProtKB | ChEBI)
Binding site155Mn2+ 1 (UniProtKB | ChEBI)
Binding site157Mn2+ 1 (UniProtKB | ChEBI)
Binding site157Mn2+ 2 (UniProtKB | ChEBI)
Binding site159Mn2+ 1 (UniProtKB | ChEBI)
Binding site241Mn2+ 1 (UniProtKB | ChEBI)
Binding site241Mn2+ 2 (UniProtKB | ChEBI)
Binding site243Mn2+ 1 (UniProtKB | ChEBI)
Binding site243Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionformimidoylglutamase activity
Molecular Functionmanganese ion binding
Biological ProcessL-histidine catabolic process to glutamate and formamide
Biological ProcessL-histidine catabolic process to glutamate and formate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formimidoylglutamase
  • EC number
  • Alternative names
    • Formiminoglutamase
    • Formiminoglutamate hydrolase

Gene names

    • Name
      hutG
    • ORF names
      AN232_22490

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AR_0157
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Citrobacter

Accessions

  • Primary accession
    A0A2Z3XCX8

Proteomes

Family & Domains

Sequence similarities

Belongs to the arginase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    33,806
  • Last updated
    2018-10-10 v1
  • Checksum
    52D1029DF0B9D666
MTNWQPASPALWQGRDDRAESPTALRLFQTITLSPAFSPEMHSEQIALLGFACDEGVKRNQGRTGAAGAPDALRKALANLASHDGHQRLVDLGNIVAQAPDLEGAQQALRKAVQRCQQAKMRTLVLGGGHETAFAHGAGVLDAFPQAKVGIINLDAHLDLRHAEQATSGTPFRQLAHLCDEQQRGFHYACIGVSRAANTQALWDEAQRLGVTVVEDLHCDSAQAQLAQFASGADVIYLTIDLDVLPVWEMPAVSAPAALGVPLATLLGLIEPLCRSGKLQAVDMVEFNPRFDDDGRAARVAARLGWQIAHWWR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP029727
EMBL· GenBank· DDBJ
AWS97777.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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