A0A2X0LNV1 · A0A2X0LNV1_9BASI

  • Protein
    JmjC domain-containing histone demethylation protein 1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionhistone H3K36me/H3K36me2 demethylase activity
Molecular Functionmetal ion binding
Molecular Functiontranscription coregulator activity
Biological Processregulation of transcription by RNA polymerase II

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    JmjC domain-containing histone demethylation protein 1
  • EC number
  • Alternative names
    • [Histone-H3]-lysine-36 demethylase 1

Gene names

    • ORF names
      BZ3500_MVSOF-1268-A1-R1_CHR9G10856

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Pucciniomycotina > Microbotryomycetes > Microbotryales > Microbotryaceae > Microbotryum

Accessions

  • Primary accession
    A0A2X0LNV1

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-175Disordered
Compositional bias48-96Polar residues
Compositional bias103-129Polar residues
Compositional bias161-175Basic and acidic residues
Domain385-549JmjC
Region740-759Disordered
Region1019-1140Disordered
Compositional bias1020-1034Basic and acidic residues
Compositional bias1039-1140Polar residues

Sequence similarities

Belongs to the JHDM1 histone demethylase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,167
  • Mass (Da)
    127,147
  • Last updated
    2018-09-12 v1
  • Checksum
    FF2B82F7CA119684
MSPTPPPVAAAAAAAAAATMDERDSSPLSTLSELDAASPPVPVPAPSSPATTSAVGPSATGTSATTSAKTSATTSSSSSSSSSTTRLTRSHSHSPSQPSRTPPPSAAAATNEPCRRSSLRSSTCTPIPAPTPATSQPATAVPRLPRLPRLPKVPSRQGTASIRRSERERRDKQRGEDVCLVCTPPGTVLTAEQEKANQDKVWIQCEHHWHCINLNAGDSPEDFDKWYCPTCIKITLATRHPLACTRRPVPRRTNRAAPKIDYANLDAHLPADHLRWQRVIATRKILPANFPKLRPERLTEEWLFKEGTWSEPIIVESPRGLGMQMPDRSTSISAIADEIGGDHPIEALDVAAQDRDRTIKTLRQWADYFENPRRDKVRNVISLEVGSTPFGEKIVAPEMVRRLDWVDNIWPKDCRDEGQYPQVQKYCLMSVAESWTIPIHQDWHIDFAGSSVFYHILRGGKVFYFIRPTKENLKAYETWSGNTDRQEANWLGDHVDAVYRVELVPGNTMFIPSGWIHAVETPSDSLVIGGNFVHSLNIETQLEVYRIELATKVPKKFRFPHFVTLLWHVANHYTARLNKVLASSASMRTWPAELRSRRVLLGLKQASEFLIEQTTRWAKGTNELSRERRRVAIHNVPNTYIKNANELSREFRQVVLRALGEPMDRLCELSNDAMSLTWVSPEEVRAEAMARDTVSTPKGKAVNGRGAAEGLTSMMNGHGDAGVKRKASDAVSLPETAAMMDPHASGTRSKKPRITPSGMTAVPNDAPTILENTTLYERRPMRTQQMMDPKRAEVGLQLAMVNESSNTKTIVKRWEEGGRVFIDVRKMITTIERVEFGVPEEEIVAAQQTLGQRGAEGADGVQGEQEIQVDGTAGSSTAGRQDIRQTTVQDLPMEVDQAPMPTVPVASTSTSALVSAPVPTPAPAPAPAPTRPPIVLAEAPAHPFPPWDPYHPTAYKLSTDPYVRLEQMSRIINTYNDPHLIKATGLNSAFMGSDGTSDADDWTDEKFFDLVWSMRPVLKEGRGTEGDSGTRRKAHGSQSKPRTSSGKMGVAFKNATQPQGPTSVPTSSLTSASTAASTSASTSASTSASTSASGSTSQAPVLETGPAATSPSLQRPDSGDVPMTSPQLKSTQPITSSPVPILSYISQNQPQLDSLAPRSTVLPAAQS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias48-96Polar residues
Compositional bias103-129Polar residues
Compositional bias161-175Basic and acidic residues
Compositional bias1020-1034Basic and acidic residues
Compositional bias1039-1140Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FMWP01000107
EMBL· GenBank· DDBJ
SDA00813.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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