A0A2V1A6R9 · A0A2V1A6R9_9ASCO

  • Protein
    tRNA-dihydrouridine(47) synthase [NAD(P)(+)]
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionmetal ion binding
Molecular FunctionmRNA dihydrouridine synthase activity
Molecular FunctionRNA binding
Molecular FunctiontRNA-dihydrouridine47 synthase activity
Biological ProcessmRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine(47) synthase [NAD(P)(+)]
  • EC number
  • Alternative names
    • tRNA-dihydrouridine synthase 3

Gene names

    • ORF names
      CXQ87_001898

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B09383
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Metschnikowiaceae > Metschnikowiaceae incertae sedis > Candida/Metschnikowiaceae

Accessions

  • Primary accession
    A0A2V1A6R9

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for compositional bias, region, domain, zinc finger.

TypeIDPosition(s)Description
Compositional bias1-28Basic and acidic residues
Region1-90Disordered
Domain82-114C3H1-type
Zinc finger82-114C3H1-type

Sequence similarities

Belongs to the dus family. Dus3 subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    602
  • Mass (Da)
    68,423
  • Last updated
    2018-09-12 v1
  • Checksum
    D6AD94D8E06DD0DE
MTEDDKRDIDASTEPVAKKARTDNYDKGLAPIKPEFVVESVKVEEAYDDEEAEGGDRGQQEGSKRSKKKRGQNKKRDLKQQKEDVRLCSSLVDPSDPKECKFGPDKCRNTHDVTYYLSTKPDDIEGKCPVQVAIGYCPAGLKCRWLSSHYNKDTNELLKEEPKTDNYELNKISADHRMDLQKHRYIFEKADAYNKYLDSLVKNDANAKKQEEVKDNAASYVEPPFKPAEKKRLNFDRAKIVSPLTTVGNLPYRRLMKTLGADVTYSEMALSLPLLQGTKPEWALPKAHVSEYPGFGVQLAANHHQQASKAAEAVYNEASHVSELNLNCGCPIDLLYRQGQGSALLDQPAKLVRILNGMNACSGDIPVTFKIRTGTKDNKNTAISLVNRVLTETDVAAVTLHGRSRQQRYTREADWGYVGEVARSVKELNEKKQENKDLTDTQPTWFIGNGDCFTHEQWYEAVNTEGIDSVMVARGALIKPWIFEEIEAQQYLDKSATERLEHLRTFANFAVEHWGSDEYGIEVARRFLCEFIGFTHRYIPVGILEKLPPKLNQRPPKWRGRNELETLLGSTDYKDWIKITEMFLGKASPNFQFVPKHKSNSY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-28Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PKFP01000001
EMBL· GenBank· DDBJ
PVH13780.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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