A0A2U9CPN6 · A0A2U9CPN6_SCOMX

Function

function

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentmRNA cleavage and polyadenylation specificity factor complex
Molecular Functionmetal ion binding
Molecular FunctionRNA binding
Biological ProcessmRNA 3'-end processing

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cleavage and polyadenylation specificity factor subunit 4
  • Short names
    CPSF 30 kDa subunit
  • Alternative names
    • Cleavage and polyadenylation specificity factor 30 kDa subunit

Gene names

    • ORF names
      SMAX5B_006601

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Carangaria > Pleuronectiformes > Pleuronectoidei > Scophthalmidae > Scophthalmus

Accessions

  • Primary accession
    A0A2U9CPN6

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Subunit

Component of the cleavage and polyadenylation specificity factor (CPSF) complex.

Family & Domains

Features

Showing features for domain, zinc finger, region, compositional bias.

TypeIDPosition(s)Description
Domain35-59C3H1-type
Zinc finger35-59C3H1-type
Domain62-89C3H1-type
Zinc finger62-89C3H1-type
Domain90-117C3H1-type
Zinc finger90-117C3H1-type
Domain118-145C3H1-type
Zinc finger118-145C3H1-type
Domain147-169C3H1-type
Zinc finger147-169C3H1-type
Region175-196Disordered
Compositional bias177-196Polar residues

Sequence similarities

Belongs to the CPSF4/YTH1 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    196
  • Mass (Da)
    22,421
  • Last updated
    2018-09-12 v1
  • Checksum
    ADEF9DD9211AF1E2
MQDLLASADHIKFDLEIAVEQQLGAQPLPFPGMDKSGSAVCEFFMRAACIKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPDCRHRHTRRVICMNYLVGFCPEGKSCKFMHPRFELPMGASEQPPLQQQAQNQIKPLCSTG

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2U9CPV8A0A2U9CPV8_SCOMXcpsf4266
A0A2U9CSE1A0A2U9CSE1_SCOMXSMAX5B_006601213

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias177-196Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP026261
EMBL· GenBank· DDBJ
AWP18604.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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