A0A2U0I252 · A0A2U0I252_9FLAO

Function

function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site72FMN (UniProtKB | ChEBI)
Active site102Proton donor
Binding site141FMN (UniProtKB | ChEBI)
Binding site171FMN (UniProtKB | ChEBI)
Binding site228-229FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionRNA binding
Molecular FunctiontRNA dihydrouridine synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine synthase
  • EC number

Gene names

    • ORF names
      DDV96_07225

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HN-E44
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Marixanthomonas

Accessions

  • Primary accession
    A0A2U0I252

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-313DUS-like FMN-binding

Sequence similarities

Belongs to the dus family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    330
  • Mass (Da)
    37,080
  • Last updated
    2018-07-18 v1
  • Checksum
    E7A6065BAB389A0F
MAKIGNIDVGDFPLLLAPMEDVSDPPFRALCKEQGADVVYTEFISSEGLIRDAAKSVMKLDIYEKERPVGIQIFGANLDSMLQSVEIVEASGPDIIDINFGCPVKKVVSKGAGAGILKDIDLMVSLTEAMVKHTKLPVTVKTRLGWDENTIMIKEVAERLQDVGCQAISIHGRTRAQMYKGNADWKPIAEVKNNPRMHIPVFGNGDVDTPERAMEMRDKYGLDGAMIGRASIGYPWFFKEVKHYFKTGEHALPPTMEERVEAARRHLQMAIDWKGEKLGVFETRRHYTNYFKGIPDFKPYRMKMVTSDDSADVFAAFDEVLQKFGDHQFV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QEHR01000004
EMBL· GenBank· DDBJ
PVW15192.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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