A0A2T5M393 · A0A2T5M393_9EURO

Function

function

Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Protein modification; protein glycosylation.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site105Proton donor
Active site249
Active site357Proton donor
Active site391
Binding site483Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasmic vesicle lumen
Cellular Componentendoplasmic reticulum
Cellular Componentmembrane
Molecular Functioncalcium ion binding
Molecular Functionmannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Biological Processcarbohydrate metabolic process
Biological ProcessERAD pathway
Biological Processprotein glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    alpha-1,2-Mannosidase
  • EC number

Gene names

    • ORF names
      P175DRAFT_0431416

Organism names

  • Taxonomic identifier
  • Strain
    • IBT 24754
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Nidulantes

Accessions

  • Primary accession
    A0A2T5M393

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_501563231025-492alpha-1,2-Mannosidase
Disulfide bond314↔343

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Sequence similarities

Belongs to the glycosyl hydrolase 47 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    492
  • Mass (Da)
    53,672
  • Last updated
    2018-07-18 v1
  • Checksum
    15C75B519280A87E
MRLHLLALPATGLALVGSPSGSQADTVKEAFSHAWDGYMKYAFPHDELLPLSNGYGDSRNHWGASAVDALSTATIMGNATIVTQILDHIATIDYSQTASTVSLFETTIRYLAGMLSGYDLLKGPAAGLVDDNKVDVLLEQSKNLADVLKFAFDTPSGVPYNNINITSGGNDGSPTNGLAVTGTLVLEWTRLSDLTGDPEYARLSQRAESYLLHPHPASSEPFPGLVGSSISIETGNFTDGSVSWNGGDDSFYEYLIKMYVYDPKRFGVYKDRWVAAAESSMKYLASHPATRADLTFLATYNNGEYGLRSQHLACFDGGNFILGGSVLGRDDLLAFGVELVESCHETYNATVTGIGPEAFSWDSGAVPRAQAAFFDTAGFWIENGAYILRPEVIESFYYAWRITGQEEYREWIWNAFGAINKYCRTPSGFAGLTDVNAANGGSRDNNQESFLFAEVMKYSYLAFAPDDEWQVQRGGGNTFVFNTEAHPFRIST

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MSFN02000002
EMBL· GenBank· DDBJ
PTU23008.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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