A0A2K6KCY5 · A0A2K6KCY5_RHIBE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 1 Fe cation per subunit.

Pathway

Lipid metabolism.

Features

Showing features for binding site, site.

167650100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site15Ca2+ 1 (UniProtKB | ChEBI)
Binding site17Ca2+ 1 (UniProtKB | ChEBI)
Binding site39Ca2+ 2 (UniProtKB | ChEBI)
Binding site40Ca2+ 2 (UniProtKB | ChEBI)
Binding site85Ca2+ 1 (UniProtKB | ChEBI)
Binding site86Ca2+ 1 (UniProtKB | ChEBI)
Site109Essential for stabilizing binding to COTL1
Binding site373Fe cation (UniProtKB | ChEBI); catalytic
Binding site378Fe cation (UniProtKB | ChEBI); catalytic
Binding site553Fe cation (UniProtKB | ChEBI); catalytic
Binding site676Fe cation (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentcytoskeleton
Cellular Componentcytosol
Cellular Componentfocal adhesion
Cellular Componentplasma membrane
Molecular Functionarachidonate 15-lipoxygenase activity
Molecular Functionarachidonate 8(S)-lipoxygenase activity
Molecular Functioncalcium ion binding
Molecular Functioniron ion binding
Molecular Functionlinoleate 13S-lipoxygenase activity
Molecular Functionlinoleate 9S-lipoxygenase activity
Biological Processarachidonic acid metabolic process
Biological Processcannabinoid biosynthetic process
Biological Processendocannabinoid signaling pathway
Biological Processhepoxilin biosynthetic process
Biological Processlinoleic acid metabolic process
Biological Processlipid oxidation
Biological Processlipoxin A4 biosynthetic process
Biological Processlipoxygenase pathway
Biological Processnegative regulation of cell cycle
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of growth
Biological Processphospholipid metabolic process
Biological Processpositive regulation of chemokine production
Biological Processpositive regulation of keratinocyte differentiation
Biological Processpositive regulation of macrophage derived foam cell differentiation
Biological Processpositive regulation of peroxisome proliferator activated receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Arachidonate 15-lipoxygenase type B

Gene names

    • Name
      ALOX15B

Organism names

Accessions

  • Primary accession
    A0A2K6KCY5

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-124PLAT
Domain124-676Lipoxygenase

Sequence similarities

Belongs to the lipoxygenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    676
  • Mass (Da)
    75,917
  • Last updated
    2018-03-28 v1
  • Checksum
    3965741C4B0864E0
MADFRVRVSTGKAFGAGTWDKVSVSIVGTREESPPMPLDNLGKEFTAGTEEDFQVTLPKDVGQVLLLRLHKAPPALPLLGPLAPDAWFCRWFQLTPPQGGPLLFPCYQWLEGAGSLVLQEGTAKVSRADHHPLLQQQRQEELQARQEMYQWKAYNPGWPHCLDKRTVKDLDLNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRKTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIHTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQSPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINMLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMRIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFNCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATREGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIAAFQSHLAQISRAIQERNRGLVLPYTYLDPPLIENSVSI

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2K6KCV8A0A2K6KCV8_RHIBEALOX15B602
A0A2K6KCX7A0A2K6KCX7_RHIBEALOX15B647

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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