A0A2K5II69 · A0A2K5II69_COLAP
- ProteinCholesteryl ester transfer protein
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids428 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
Catalytic activity
- 1,2,3-tri-(9Z-octadecenoyl)-glycerol(in) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol(out)
- cholesteryl (9Z,12Z)-octadecadienoate(in) = cholesteryl (9Z,12Z)-octadecadienoate(out)
- cholesteryl (9Z-octadecenoate)(in) = cholesteryl (9Z-octadecenoate)(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | high-density lipoprotein particle | |
Molecular Function | cholesterol transfer activity | |
Molecular Function | lipid binding | |
Biological Process | cholesterol metabolic process | |
Biological Process | high-density lipoprotein particle remodeling | |
Biological Process | reverse cholesterol transport | |
Biological Process | triglyceride transport | |
Biological Process | very-low-density lipoprotein particle remodeling |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCholesteryl ester transfer protein
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Colobinae > Colobus
Accessions
- Primary accessionA0A2K5II69
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 95↔136 | |||||
Sequence: CYLSFHKLLLQLQGEREPGWIKQLFTNFISFTLKLVLKGQIC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-193 | Lipid-binding serum glycoprotein N-terminal | ||||
Sequence: MMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFMGTLKYGYTTAWGLGIDQSIDFEIDSAIDLQINTQLTCHSGRVRTDAPDCYLSFHKLLLQLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPIITASHLESHHKGYFIYKNV | ||||||
Domain | 207-411 | Lipid-binding serum glycoprotein C-terminal | ||||
Sequence: LGDSRMLYFWFSEQVFHSLAKVAFQDGRLTLSLMGDEFKAVLETWGFNTNQEIFREVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSLVMVKFLFPRPDQQHSVAYTFEEDITTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSKSVQSFLQSMITTVGIPEVMSRLEAVFTALMNSKGLSLFDIINPEIITRDGFLLLQM |
Sequence similarities
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length428
- Mass (Da)47,841
- Last updated2018-03-28 v1
- Checksum8BC20414A883CDE9
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2K5II85 | A0A2K5II85_COLAP | 493 | |||
A0A2K5IIP0 | A0A2K5IIP0_COLAP | 433 | |||
A0A2K5II45 | A0A2K5II45_COLAP | 491 |
Keywords
- Technical term