A0A2J7W4K8 · A0A2J7W4K8_9BURK
- ProteinMethionyl-tRNA formyltransferase
- Genefmt
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids317 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
Catalytic activity
- L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | methionyl-tRNA formyltransferase activity |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionyl-tRNA formyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Variovorax
Accessions
- Primary accessionA0A2J7W4K8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-187 | Formyl transferase N-terminal | ||||
Sequence: MRIAFAGTPEFARVALEAIAAAGFEIVLVLTQPDRPAGRGMKLQASPVKQFAAARGWPVAQPRSLRLDGKYPEDAAAARAAILDARLDAMVVAAYGLILPQWVLDAPRLGCLNIHASLLPRWRGAAPIHRAIEAGDAQTGVTIMQMDAGLDTGDMLLRESLAIGDGSTAQLHDRLAGLGGRLIVDAL | ||||||
Domain | 210-308 | Formyl transferase C-terminal | ||||
Sequence: KVEKQEAQIDWRTHDAAAIVRRIRAFDPFPGASSTLDGETLKLWAAQVRLDPPGQPPGTVLAVGPAGVAVAARDAVVVLTELQRPGGKRLAVADFLRGF |
Sequence similarities
Belongs to the Fmt family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length317
- Mass (Da)33,589
- Last updated2018-03-28 v1
- Checksum913F2BFE42E4F915