A0A2E7FHS1 · A0A2E7FHS1_9FLAO

Function

function

Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site47-54ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functiontetraacyldisaccharide 4'-kinase activity
Biological Processlipid A biosynthetic process
Biological Processlipopolysaccharide core region biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tetraacyldisaccharide 4'-kinase
  • EC number
  • Alternative names
    • Lipid A 4'-kinase

Gene names

    • Name
      lpxK
    • ORF names
      CMC80_05800

Organism names

Accessions

  • Primary accession
    A0A2E7FHS1

Proteomes

Subcellular Location

Family & Domains

Sequence similarities

Belongs to the LpxK family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    332
  • Mass (Da)
    37,836
  • Last updated
    2018-04-25 v1
  • Checksum
    D1BE851AD7B68AB4
MNLLRKSLFPLSLLYDVVTRVRNAAFDKQWLHQSQFAVPTIVIGNLITGGSGKTPMIAYLLHQFSDRFSFAVLSRGYKRKSSGFFVADETSSIETLGDEPFLLFQKFPKVQFAVCKNRPNGIRGLLQKSPQLDAIFLDDGFQHRQLKPSFQILLTPFETPWFRDCVLPAGNLRESARGKKRADLVVVTKCPELLSKKEREDYTNQLALDPDQNLFFTSIQYDTNVCGASQMELKSFVQSPFVLVTGIANAKPLTSYLDQLDAKYKHLEFGDHHSFSPSDRQNILSSGLPVLTTEKDYVRLNPYLKDVHYLPISVRFLADEDRFKDIISNQIR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PBNJ01000021
EMBL· GenBank· DDBJ
MBN11026.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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