A0A2E0F649 · A0A2E0F649_9FLAO

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.

Features

Showing features for binding site.

147250100150200250300350400450
TypeIDPosition(s)Description
Binding site217Mg2+ 2 (UniProtKB | ChEBI)
Binding site217Mg2+ 1 (UniProtKB | ChEBI)
Binding site221Mg2+ 1 (UniProtKB | ChEBI)
Binding site389Mg2+ 2 (UniProtKB | ChEBI)
Binding site393Mg2+ 2 (UniProtKB | ChEBI)
Binding site414substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionisomerase activity
Molecular Functionketol-acid reductoisomerase activity
Molecular Functionmetal ion binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ketol-acid reductoisomerase
  • EC number

Gene names

    • ORF names
      CMC45_04945

Organism names

Accessions

  • Primary accession
    A0A2E0F649

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain17-208KARI N-terminal Rossmann
Domain209-343KARI C-terminal knotted
Domain345-472KARI C-terminal knotted

Sequence similarities

Belongs to the ketol-acid reductoisomerase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    472
  • Mass (Da)
    53,038
  • Last updated
    2018-04-25 v1
  • Checksum
    8A49A313010B6023
MGNYFNKLSEIEKRNQLNMCRFMNNDEFSDGVNALLGKKIVIVGCGAQGLNQGLNMRDSGLDISYVLRQSSIDSKKESYLNAKENNFNVGNFEDLIPEADIVINLTPDKNHTNVVSNVVPLMKKNSVLSFSHGFNIVEEGTIVRNDITVIMVAPKCPGTEVREEYLRGFGVPTLIAVHPENDPHNNGLELAKAYAVATGGHRAGVLESSFVAEVKSDLMGEQTILCGVLQTGSLLCFEKMLSLGFDKSFSVKLIQFGWETITEELKHNGITGMINRLDDKSRYAVHELSEQLKDIMTPLFNKHMNDILDGTFSTGMMKDWENDDHNLLKWREETGDTLFEKTPSGSENISNQDFFDKGILMIAFVKSGVELAFETMVNNGIIDESAYYESLHELPLIANLVARKKLYEMNRIISDTAEYGCYLFNHECLPLLKGFMNELERGFIGENIPNSYTFNEEKLNEYDNLTSSHPIE

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue472

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NZZF01000055
EMBL· GenBank· DDBJ
MAR63164.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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