A0A2D4K4A2 · A0A2D4K4A2_9SAUR
- ProteinPhosphoglucomutase-1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids494 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. This enzyme participates in both the breakdown and synthesis of glucose.
Catalytic activity
- alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate
- O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphoglucomutase activity | |
Biological Process | carbohydrate metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoglucomutase-1
- EC number
- Alternative names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Episquamata > Toxicofera > Serpentes > Colubroidea > Elapidae > Elapinae > Micrurus
Accessions
- Primary accessionA0A2D4K4A2
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-134 | Alpha-D-phosphohexomutase alpha/beta/alpha | ||||
Sequence: RVKVFQGNAHYAENFIQSIISTIEPAERQAATLVVGGDGRFYMKEAIQLILRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTSNGGPAPEGITDKIFQISKTIEEY | ||||||
Domain | 171-277 | Alpha-D-phosphohexomutase alpha/beta/alpha | ||||
Sequence: AYANMLRNIFDFSALKELLSGPNHLKIRIDAMHGVVGPYVKQILCEELGAAANSAVNCVPLEDFGGHHPDPNLTYAADLLQTMKTGEYDFGAAFDGDGDRNMILGKH | ||||||
Domain | 284-397 | Alpha-D-phosphohexomutase alpha/beta/alpha | ||||
Sequence: SDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSIIATRKQSVESILKDHWQQY |
Sequence similarities
Belongs to the phosphohexose mutase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length494
- Mass (Da)53,996
- Last updated2018-01-31 v1
- ChecksumDA8019BF78CF8DFB
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: K | ||||||
Non-terminal residue | 494 | |||||
Sequence: Y |