A0A2D0S9U6 · A0A2D0S9U6_ICTPU
- ProteinProtein phosphatase 1bb isoform X1
- Geneppm1bb
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids463 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | membrane | |
Cellular Component | nucleus | |
Molecular Function | magnesium ion binding | |
Molecular Function | manganese ion binding | |
Molecular Function | myosin phosphatase activity | |
Biological Process | negative regulation of canonical NF-kappaB signal transduction | |
Biological Process | peptidyl-threonine dephosphorylation | |
Biological Process | positive regulation of canonical NF-kappaB signal transduction | |
Biological Process | positive regulation of canonical Wnt signaling pathway |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Siluriformes > Ictaluridae > Ictalurus
Accessions
- Primary accessionA0A2D0S9U6
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | ||||
Sequence: MGAFLDKPKTEKHNAH | ||||||
Region | 1-20 | Disordered | ||||
Sequence: MGAFLDKPKTEKHNAHGAGN | ||||||
Domain | 23-290 | PPM-type phosphatase | ||||
Sequence: RFGLSSMQGWRVEMEDAHTAVVGLPHGLDDWSFFAVYDGHAGSRVANYCSKHLLEHIISSNEDFRPGHDSVEGVKSGIRSGFLKIDEYMRNFSELRNGMDRSGSTAVGVLLSPEHLYFINCGDSRAVLCRAGQVRFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVFEIPRVPDEDEFVVLACDGIWDVMSNEELCEFVHSRLEVCDDLEKVCNSVVDTCLHKGSRDNMSVVLVCL | ||||||
Compositional bias | 367-381 | Basic and acidic residues | ||||
Sequence: PHREDDGDDQGGAAG | ||||||
Region | 367-387 | Disordered | ||||
Sequence: PHREDDGDDQGGAAGEDEKSS | ||||||
Compositional bias | 420-441 | Polar residues | ||||
Sequence: LSSAQEERPLHPPSTTSEPLNS | ||||||
Region | 420-463 | Disordered | ||||
Sequence: LSSAQEERPLHPPSTTSEPLNSDDGAEEAAMPPALDELSNPPVA |
Sequence similarities
Belongs to the PP2C family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length463
- Mass (Da)50,852
- Last updated2017-12-20 v1
- Checksum0655F163699F57B6
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | ||||
Sequence: MGAFLDKPKTEKHNAH | ||||||
Compositional bias | 367-381 | Basic and acidic residues | ||||
Sequence: PHREDDGDDQGGAAG | ||||||
Compositional bias | 420-441 | Polar residues | ||||
Sequence: LSSAQEERPLHPPSTTSEPLNS |