A0A223XPX7 · A0A223XPX7_LEUME
- ProteinGlucose-6-phosphate 1-dehydrogenase
- Genezwf
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids486 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
Catalytic activity
- D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + H+ + NADPH
Pathway
Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 13-20 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: GGTGDLAK | ||||||
Binding site | 47 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 86-87 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: DV | ||||||
Binding site | 149 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 179 | substrate | ||||
Sequence: H | ||||||
Binding site | 183 | substrate | ||||
Sequence: K | ||||||
Binding site | 217 | substrate | ||||
Sequence: E | ||||||
Binding site | 236 | substrate | ||||
Sequence: D | ||||||
Active site | 241 | Proton acceptor | ||||
Sequence: H | ||||||
Binding site | 339 | substrate | ||||
Sequence: K | ||||||
Binding site | 344 | substrate | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glucose-6-phosphate dehydrogenase activity | |
Molecular Function | NADP binding | |
Biological Process | glucose metabolic process | |
Biological Process | pentose-phosphate shunt |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucose-6-phosphate 1-dehydrogenase
- EC number
- Short namesG6PD
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Leuconostoc
Accessions
- Primary accessionA0A223XPX7
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length486
- Mass (Da)54,575
- Last updated2017-10-25 v1
- ChecksumF0EA29B0AFAED40A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WIPA01000002 EMBL· GenBank· DDBJ | MQR26122.1 EMBL· GenBank· DDBJ | Genomic DNA |