A0A1I1DC51 · A0A1I1DC51_9BACT

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site58substrate
Binding site134substrate
Binding site159substrate
Binding site160-162NAD+ (UniProtKB | ChEBI)
Binding site189substrate
Binding site193substrate
Binding site194NAD+ (UniProtKB | ChEBI)
Binding site223-228NAD+ (UniProtKB | ChEBI)
Binding site225-230NAD+ (UniProtKB | ChEBI)
Binding site246NAD+ (UniProtKB | ChEBI)
Binding site281NAD+ (UniProtKB | ChEBI)
Binding site302-304NAD+ (UniProtKB | ChEBI)
Binding site349NAD+ (UniProtKB | ChEBI)
Binding site356NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      SAMN05421780_10183

Organism names

Accessions

  • Primary accession
    A0A1I1DC51

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain194-355S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    435
  • Mass (Da)
    48,192
  • Last updated
    2017-11-22 v1
  • Checksum
    A2CF71734E60C12C
MVQTYQKYKVKDISLAEWGRKEIRLAEAEMPGLMALRTEYGPSKPLKGARIAGCLHMTIQTAVLIETLIELGAEVTWSSCNIFSTQDHAAAAIAAAGISVYAWKGMNAEEFDWCIEQTLFFGEDRKPLNMILDDGGDLTNMVFDKYKELIPAIKGLSEETTTGVHRLYERMKKGTLYLPAINVNDSVTKSKFDNLYGCKESCVDAIRRATDVMMAGKVAVVAGFGDVGKGSAKSLRGAGARVIVTEIDPICALQAAMEGYQVMKMDKAAELGDIFVTATGNMNIITERHFRKMRDKAIVCNIGHFDTEIDMAWLNNNYGSTKVEVKPQVDIYNVDGKEVIVLAEGRLVNLGCATGHPSFVMSNSFCNQTLAQLELWTNTDKYENQVYTLPKHLDEKVARLHLGKIGVELDELSTEQAEYIGVAVQGPFKAEMYRY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FOLE01000001
EMBL· GenBank· DDBJ
SFB71916.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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