A0A1E1WGW3 · A0A1E1WGW3_PECGO

Function

function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentMICOS complex
Biological Processcristae formation

Names & Taxonomy

Protein names

  • Recommended name
    MICOS complex subunit MIC60
  • Alternative names
    • Mitofilin

Gene names

    • ORF names
      g.1397

Organism names

Accessions

  • Primary accession
    A0A1E1WGW3

Subcellular Location

Mitochondrion inner membrane
; Single-pass membrane protein

Keywords

Interaction

Subunit

Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-22Disordered

Sequence similarities

Belongs to the MICOS complex subunit Mic60 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    607
  • Mass (Da)
    69,407
  • Last updated
    2017-01-18 v1
  • Checksum
    987F10043A533B6F
MLNIARRRATGWSPTPPGPTTSWPFVYQENTTYVQFTIDQVSRMSKALTTFLFGKEGVSPMDFQQRSEQDIEKDAEIGFQPKEYSLPVPTLEPLYVEEKVIGTPEVEHEATLVQTEKCDPHSPPKTNITKDILILEQDMHENTKIAIDNYKAALKLCTAYNKTLHRIVEFPYEDLDKKCFAKLKGLRAERDKTIATAKAASTKAKCALETLDRMIEKNNIAAPPENVTQTKRYIKLFRNDLTVAEDAVRDELTKAVISDKYWDRVEAARMAYKEELEMLFPGLDLCSRQLEFRGDVDLLLLYTMNQIQYLQNQLAENQTIREHKINKAIECRDEKAIIEAKVEDMIRKERLTKDLEFQKKTLEINAEAKKKMKEELARQFEIQEEITRTRLARKEAEIMGKFNRQVSELVEKERVIFKKELAAMAGKLKAIEQTLKQRAAAEAEARRSQSIWAAAEALLAATRRASSETKIDNELRALEKAGEGDKLVQTILKGIPPEVRDKGISTEKSLRDRFEVLEQTAMKVALIGREGASLPMYFISWLQSKLLFQKLAEIPRDELDNLPTDFSKLDTFDIIHRARYHMDNGDLPAALRYVNLLQGAARAAAAC

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue607

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GDQN01004832
EMBL· GenBank· DDBJ
JAT86222.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

Disclaimer

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