A0A1A8RFF2 · A0A1A8RFF2_9TELE
- ProteinAurora kinase
- GeneAURKA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids235 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome passenger complex | |
Cellular Component | cytoplasm | |
Cellular Component | kinetochore | |
Cellular Component | spindle microtubule | |
Cellular Component | spindle midzone | |
Cellular Component | spindle pole centrosome | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization | |
Biological Process | regulation of cytokinesis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAurora kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Cyprinodontiformes > Nothobranchiidae > Nothobranchius
Accessions
- Primary accessionA0A1A8RFF2
Subcellular Location
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-135 | Disordered | ||||
Sequence: MDSSTTQKVAGLVKPPRPVVKSSGDGPSRVPVSRNSKAVVTPTQPRVLGVSNGPQRVQRPVSHKKPVSQVSVVKSNQPSDQNANPATPCSNPPQPKPVSQQNQPKTHVPSAKPPSDPAKQAKPQNKPAKTNQVAP | ||||||
Compositional bias | 28-87 | Polar residues | ||||
Sequence: SRVPVSRNSKAVVTPTQPRVLGVSNGPQRVQRPVSHKKPVSQVSVVKSNQPSDQNANPAT | ||||||
Domain | 145-235 | Protein kinase | ||||
Sequence: FDIGRPLGKGKFGNVYLARERQTKFILALKVLFKNQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEFAPKGELYGELQ |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusFragment
- Length235
- Mass (Da)25,987
- Last updated2016-10-05 v1
- Checksum65F8ED6C51D2D3A6
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 28-87 | Polar residues | ||||
Sequence: SRVPVSRNSKAVVTPTQPRVLGVSNGPQRVQRPVSHKKPVSQVSVVKSNQPSDQNANPAT | ||||||
Non-terminal residue | 235 | |||||
Sequence: Q |