A0A176TDT9 · A0A176TDT9_9FLAO

  • Protein
    Tetraacyldisaccharide 4'-kinase
  • Gene
    lpxK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site47-54ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functiontetraacyldisaccharide 4'-kinase activity
Biological Processlipid A biosynthetic process
Biological Processlipopolysaccharide core region biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tetraacyldisaccharide 4'-kinase
  • EC number
  • Alternative names
    • Lipid A 4'-kinase

Gene names

    • Name
      lpxK
    • ORF names
      LPB303_04020

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KACC 17473
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae

Accessions

  • Primary accession
    A0A176TDT9

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the LpxK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    337
  • Mass (Da)
    38,833
  • Last updated
    2016-09-07 v1
  • Checksum
    DAC52368394E448A
MKFLRFLLFPFAIIYDVVTSIRNFFFEVGFFKQTSFKVPVIVVGNLSVGGTGKTPQIEYLIRLLKDRFKTVVLSRGYKRKTEGFVLLNSTHSAEDVGDEPLQYFKKFDSIDVAVDANRVQGITKLIADKSPEVILLDDAYQHRKVKGSFYILLTKFDDLFTDDFLLPTGNLRESRRGAKRADVILVTKCPVHLSEYSKNKIEEKLRKYDKEVFFTSISYDDKTAGSEAILIDDLKKYEVLLITGIANPTPLLSFLKEKEVNFKHLKFSDHHHFTDNEISVIKQEFTDLKSSKKLVLTTEKDYVRLESRLEQLSFLGIQTSFLAQEEIFNAILKNHIQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LVWE01000005
EMBL· GenBank· DDBJ
OAD46087.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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