A0A101ERS2 · A0A101ERS2_9THEM

  • Protein
    Methylthioribose-1-phosphate isomerase
  • Gene
    mtnA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site48-50substrate
Binding site88substrate
Site154Transition state stabilizer
Binding site193substrate
Active site234Proton donor
Binding site244-245substrate

GO annotations

AspectTerm
Molecular FunctionS-methyl-5-thioribose-1-phosphate isomerase activity
Biological ProcessL-methionine salvage from methylthioadenosine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribose-1-phosphate isomerase
  • EC number
  • Short names
    M1Pi
    ; MTR-1-P isomerase
  • Alternative names
    • S-methyl-5-thioribose-1-phosphate isomerase

Gene names

    • Name
      mtnA
    • ORF names
      XD57_0408

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 46_26
  • Taxonomic lineage
    Bacteria > Thermotogota > Thermotogae > Thermotogales > Thermotogaceae > Thermotoga

Accessions

  • Primary accession
    A0A101ERS2

Proteomes

Family & Domains

Sequence similarities

Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    343
  • Mass (Da)
    38,013
  • Last updated
    2016-04-13 v1
  • Checksum
    E3EB622540AD4D01
MKLKTKTMEWSGDSLKLLDQRKLPFIEEYVECKTHEEVAHAIKEMIVRGAPAIGVTAAFGYVLGLRDYKTGSLTDWMKQVKETLARTRPTAVNLFWALNRMEKVFFENVDRENLFEILENEALKMAYEDIEVNKAIGKNGAQLIKDGSTILTHCNAGALATVDYGTALGVIRAAMESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKKGLIDAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIKSGEEIPIEERRPEEVTHCGGNRIAPEGVKVLNPAFDVTENTLITAIITEKGVIRPPFEENIKKILGV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LGFG01000020
EMBL· GenBank· DDBJ
KUK23492.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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