A0A0R3CVX7 · A0A0R3CVX7_9BRAD

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Divalent metal cations. Prefers magnesium or manganese.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for active site, binding site.

153150100150200250300350400450500
TypeIDPosition(s)Description
Active site87Proton donor
Binding site139substrate
Active site157Proton acceptor
Binding site228a divalent metal cation (UniProtKB | ChEBI)
Binding site229a divalent metal cation (UniProtKB | ChEBI)
Binding site252a divalent metal cation (UniProtKB | ChEBI)
Binding site392substrate
Binding site436substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionmalic enzyme activity
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Malate dehydrogenase

Gene names

    • ORF names
      AOQ72_10035
      , GA0061099_1007533

Organism names

  • Taxonomic identifier
  • Strains
    • BR3267
    • CCBAU 10071
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Nitrobacteraceae > Bradyrhizobium

Accessions

  • Primary accession
    A0A0R3CVX7

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain64-243Malic enzyme N-terminal
Domain253-505Malic enzyme NAD-binding

Sequence similarities

Belongs to the malic enzymes family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    531
  • Mass (Da)
    57,426
  • Last updated
    2016-01-20 v1
  • Checksum
    F5A8DDCD04D3CA87
MTLLRDPLLNKGTAFTEAERAALGLRGLLPPCVLTMETQAQRVLTNLRTLPTDLEKYVALNALHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEILKNWPYQARLIVVTDGERILGLGDLGANGMGIPVGKLSLYSACAGVHPEACLPIVLDVGTNNEELLNDPYYLGLRERRLTGEAYDSFVDEFMQAARKTFPGVLIQFEDFANHSAFKLLHKYRDEACVFNDDIQGTAAVALAGLFSALRISGGKLKDQKILFLGAGEAATGIADLVVSAMMAEGASEADALRRNWLVDSRGLVVSGREGLSGHKLRYAHAGQAPIADFLTAIKTLKPTAIIGVAAVGGAFTPDVLKAMAELNEQPIVFALSNPTSKAECSAEDAYRYTEGRALFACGSPYDPVKLNGRSFVPRQGNNSYIFPGVGLGVIASRSRLVTDEMFMAAAHALADCVGKEDLAQGSLYPALPRIREVSVRIAAAVADVAYQRALADGPAPNDVKALVQSQMYEPKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LJYF01000004
EMBL· GenBank· DDBJ
KRQ01760.1
EMBL· GenBank· DDBJ
Genomic DNA
FMAE01000007
EMBL· GenBank· DDBJ
SCB44467.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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