A0A0P6WPA3 · A0A0P6WPA3_9CHLR
- ProteinMethionine--tRNA ligase
- GenemetG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids594 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Catalytic activity
- tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | methionine-tRNA ligase activity | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Chloroflexota > Anaerolineae > Anaerolineales > Anaerolineaceae > Leptolinea
Accessions
- Primary accessionA0A0P6WPA3
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-412 | Methionyl/Leucyl tRNA synthetase | ||||
Sequence: VLVSVAWPYANAEIHVGNITGAYLPADIFARYQRLRGRKVLMVSGSDSHGTPITVRADAEKTTPLEVYQRYHNSFLDLFKELGLTYDLFTSTHTSNHFDVSQKIFLSLQKNGYLYTDRELQWYAPSQKRFLPDRYVEGTCYICGFENARSDQCDKCGNLLDPAQLINPRSKVDGSTPELRETEHTYLDLGKLQPAVVEFLKQRESYWRPNVLRQSLGQILADNLHGRAITRDLDWGIPVPLEGWDGKCLYVWFEAVIGYLSASIEWSKLIGKPDAWTEWWHGPQSQAYYFIGKDNIPFHAVIWPAQLTGSGKAFDELMGLPNPAPLNLPYDVPANEFMNLENQKISGSRNWAVWGRDFLTRYDPDPLRYYLTVNMPESKDTDWDWEDFFHRNNDELVATWGNLANRVL | ||||||
Motif | 12-22 | 'HIGH' region | ||||
Sequence: PYANAEIHVGN | ||||||
Domain | 423-525 | Methionyl-tRNA synthetase anticodon-binding | ||||
Sequence: VPDPGELTDMDKDLLAQVEKGFETVAAEMDAVHLRAALAEGMRLATEVNKYLDQTAPWSAIKTDKAAAARSVYTALKAIDSLKILLAPFLPFTSERLNGFFGN |
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length594
- Mass (Da)67,657
- Last updated2016-01-20 v1
- ChecksumD483A59FE6C8D617
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LGCK01000014 EMBL· GenBank· DDBJ | KPL70588.1 EMBL· GenBank· DDBJ | Genomic DNA |