A0A0H3MCT1 · A0A0H3MCT1_ECO7I

Function

function

Cell wall formation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site15
Active site150
Binding site257Mg2+ 1 (UniProtKB | ChEBI)
Binding site270Mg2+ 2 (UniProtKB | ChEBI)
Binding site270Mg2+ 1 (UniProtKB | ChEBI)
Binding site272Mg2+ 2 (UniProtKB | ChEBI)
Active site281

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionD-alanine-D-alanine ligase activity
Molecular Functionmetal ion binding
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    D-alanine--D-alanine ligase
  • EC number
  • Alternative names
    • D-Ala-D-Ala ligase
    • D-alanylalanine synthetase

Gene names

    • Name
      ddlB
    • Synonyms
      ddl
    • Ordered locus names
      ECIAI39_0095

Organism names

Accessions

  • Primary accession
    A0A0H3MCT1

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain101-303ATP-grasp

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    32,870
  • Last updated
    2015-09-16 v1
  • Checksum
    FEB50CAE53BC3D14
MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVTLTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU928164
EMBL· GenBank· DDBJ
CAR16236.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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