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Entry version 33 (17 Jun 2020)
Sequence version 1 (24 Jun 2015)
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Protein
Submitted name:

Deoxyribonuclease

Gene

tatD

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DeoxyribonucleaseImported (EC:3.1.21.-Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tatDImported
ORF Names:ERS007661_00198Imported, ERS007665_01212Imported, ERS007722_01617Imported, ERS013471_01417Imported, ERS023446_01705Imported, ERS024276_02710Imported, ERS027659_01373Imported, SAMEA2683035_03117Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000039953 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000049989 Componenti: Unassembled WGS sequence
  • UP000039217 Componenti: Unassembled WGS sequence
  • UP000045274 Componenti: Unassembled WGS sequence
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 21DisorderedSequence analysisAdd BLAST21

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01310 TatD_DNAse, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018228 DNase_TatD-rel_CS
IPR015991 Hydrolase_TatD-type
IPR032466 Metal_Hydrolase
IPR001130 TatD_family

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01026 TatD_DNase, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF005902 DNase_TatD, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51556 SSF51556, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00010 TIGR00010, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01091 TATD_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0E7YUK4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRVSSDRPAR RDPPPAPEPL APLVDAHTHL DACGARDADT VRSLVERAAA
60 70 80 90 100
AGVTAVVTVA DDLESARWVT RAAEWDRRVY AAVALHPTRA DALTDAARAE
110 120 130 140 150
LERLVAHPRV VAVGETGIDM YWPGRLDGCA EPHVQREAFA WHIDLAKRTG
160 170 180 190 200
KPLMIHNRQA DRDVLDVLRA EGAPDTVILH CFSSDAAMAR TCVDAGWLLS
210 220 230 240 250
LSGTVSFRNA RELREAVPLM PVEQLLVETD APYLTPHPHR GLANEPYCLP
260 270 280
YTVRALAELV NRRPEEVALI TTSNARRAYG LGWMRQ
Length:286
Mass (Da):31,473
Last modified:June 24, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE9F1F1E1699636F2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CNCN01000781 Genomic DNA Translation: CKP33156.1
CNFT01000245 Genomic DNA Translation: CKR42309.1
CQGE01000030 Genomic DNA Translation: CNM95716.1
CQQC01000032 Genomic DNA Translation: CNU17086.1
CQPW01000180 Genomic DNA Translation: CNU51069.1
CQTT01000028 Genomic DNA Translation: CNY38246.1
CSAM01000095 Genomic DNA Translation: COW08453.1
FPTZ01000025 Genomic DNA Translation: SGI22474.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CKP31682; CKP31682; ERS024213_01849
CKP33156; CKP33156; ERS024276_02710
CKR09935; CKR09935; ERS027644_00499
CKR42309; CKR42309; ERS027659_01373
CKS66336; CKS66336; ERS027666_01401
CKS82143; CKS82143; ERS027656_03508
CKU75606; CKU75606; ERS031537_01188
CNM95716; CNM95716; ERS023446_01705
CNU17086; CNU17086; ERS007661_00198
CNU51069; CNU51069; ERS007665_01212
CNY38246; CNY38246; ERS013471_01417
COW08453; COW08453; ERS007722_01617
CRH13157; CRH13157; BN1213_02179
CRH13632; CRH13632; BN1303_02208

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.2359.peg.3284

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CNCN01000781 Genomic DNA Translation: CKP33156.1
CNFT01000245 Genomic DNA Translation: CKR42309.1
CQGE01000030 Genomic DNA Translation: CNM95716.1
CQQC01000032 Genomic DNA Translation: CNU17086.1
CQPW01000180 Genomic DNA Translation: CNU51069.1
CQTT01000028 Genomic DNA Translation: CNY38246.1
CSAM01000095 Genomic DNA Translation: COW08453.1
FPTZ01000025 Genomic DNA Translation: SGI22474.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCKP31682; CKP31682; ERS024213_01849
CKP33156; CKP33156; ERS024276_02710
CKR09935; CKR09935; ERS027644_00499
CKR42309; CKR42309; ERS027659_01373
CKS66336; CKS66336; ERS027666_01401
CKS82143; CKS82143; ERS027656_03508
CKU75606; CKU75606; ERS031537_01188
CNM95716; CNM95716; ERS023446_01705
CNU17086; CNU17086; ERS007661_00198
CNU51069; CNU51069; ERS007665_01212
CNY38246; CNY38246; ERS013471_01417
COW08453; COW08453; ERS007722_01617
CRH13157; CRH13157; BN1213_02179
CRH13632; CRH13632; BN1303_02208
PATRICifig|1773.2359.peg.3284

Family and domain databases

CDDicd01310 TatD_DNAse, 1 hit
InterProiView protein in InterPro
IPR018228 DNase_TatD-rel_CS
IPR015991 Hydrolase_TatD-type
IPR032466 Metal_Hydrolase
IPR001130 TatD_family
PfamiView protein in Pfam
PF01026 TatD_DNase, 1 hit
PIRSFiPIRSF005902 DNase_TatD, 1 hit
SUPFAMiSSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR00010 TIGR00010, 1 hit
PROSITEiView protein in PROSITE
PS01091 TATD_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0E7YUK4_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0E7YUK4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: June 17, 2020
This is version 33 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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