A0A0A0AWZ0 · A0A0A0AWZ0_CHAVO

Function

function

Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters.

Catalytic activity

Cofactor

Cu2+ (UniProtKB | Rhea| CHEBI:29036 )

Pathway

Catecholamine biosynthesis; (R)-noradrenaline biosynthesis; (R)-noradrenaline from dopamine: step 1/1.

GO annotations

AspectTerm
Cellular Componentchromaffin granule lumen
Cellular Componentchromaffin granule membrane
Cellular Componenttransport vesicle membrane
Molecular Functioncopper ion binding
Molecular Functiondopamine beta-monooxygenase activity
Biological Processnorepinephrine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dopamine beta-hydroxylase
  • EC number

Gene names

    • ORF names
      N301_12457

Organism names

  • Taxonomic identifier
  • Strain
    • BGI_N301
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Charadriiformes > Charadriidae > Charadrius

Accessions

  • Primary accession
    A0A0A0AWZ0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homotetramer; composed of two disulfide-linked dimers.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain10-126DOMON
Region543-570Disordered
Compositional bias546-560Pro residues

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    570
  • Mass (Da)
    64,457
  • Last updated
    2015-01-07 v1
  • Checksum
    5D7B16631FF992AC
PYKVPLDPQGLLQLSWNVSYPEQVVHFQLLVRDLRFGLLFGMSDRGEFENADLAVLWSDGHNSYFGDAWSDAKGQLHMDSQQDYQLLGARKAPEGLYLLFRRAFSTCDPKDYLIEDGTVHLIYGILEKPVHSLQAINISAIHRGLQRVQLLKPNITIPELPSDMKTMEITAPNIVIPSQETTYWCYMAELPAGFSKHHIIMYEPVITVGNEALVHHMEVFQCAAKFDSFPHYNGPCDSKMKPDRLNYCRHVLAAWAMGAQAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVFKGRHDSSGIRLYFTATLRRYDAGIMELGLVYTPVMAIPPGEDAFILTGYCTDKCTQLALPAAGIRIFASQLHTHLAGRKVVTVLSRDGRERQVVNADGHYSPHFQEIRMLKELVAVYPGDELITTCTYNTEDRSRATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDPGYLHRYFNLVNRFNDEEVCTCPQVSVPQQFFSVPWNAFNRDVLKSLYGFAPISMHCNKSSAVRFPGEWEKQPLPTITERLREPVPHCPPAPGPRPSAPVPLNLGELRR

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias546-560Pro residues
Non-terminal residue570

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KL873508
EMBL· GenBank· DDBJ
KGL99069.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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