A0A091NAT2 · A0A091NAT2_APAVI

Function

Catalytic activity

  • Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.
    EC:3.4.11.7 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site, site.

165250100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site87Zn2+ (UniProtKB | ChEBI); catalytic
Active site88Proton acceptor
Binding site91Zn2+ (UniProtKB | ChEBI); catalytic
Binding site110Zn2+ (UniProtKB | ChEBI); catalytic
Site173Transition state stabilizer

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular Functionmetalloaminopeptidase activity
Molecular Functionpeptide binding
Molecular Functionzinc ion binding
Biological Processpeptide catabolic process
Biological Processproteolysis
Biological Processregulation of blood pressure

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamyl aminopeptidase
  • EC number

Gene names

    • ORF names
      N311_08003

Organism names

  • Taxonomic identifier
  • Strain
    • BGI_N311
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Coraciimorphae > Trogoniformes > Trogonidae > Apaloderma

Accessions

  • Primary accession
    A0A091NAT2

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein

Interaction

Subunit

Homodimer; disulfide-linked.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-232Peptidase M1 membrane alanine aminopeptidase
Domain310-633ERAP1-like C-terminal

Sequence similarities

Belongs to the peptidase M1 family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    652
  • Mass (Da)
    75,426
  • Last updated
    2014-11-26 v1
  • Checksum
    CA004E498F3F2D42
LRVYAQPQQISTAEYAANVTKTVFDFFEEYFNLSYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPTESATSNKQRVAAVIAHELVHQWFGNIVTMDWWDDLWLNEGFASYFEFLGVNATEPDWQMFEQVLIDDVLPVMKDDSLLSSHPIVVNVSSPAEITSVFDGISYSKGASILRMIQDWITPGLFQKGCQAYLKKYHFQNAKTQQFWEALEEASNKPVKEVMDTWTRQMGYPVLEMGDNSVLTQKRFLLDPSANASHPPSDLGYKWNIPVKWTLGNSTNYTFYNTSESAGITIPSLANSFTNINPDHIGFYRVNYDSQNWASINTLLVSNHKIFSAADRAGILDDAFSLARPGLVNYSVPLQLTKYLTSETEYLPWHRVISSVTYLSDMLKDDTNLYPRFQEYFRNLVKPIVDQLLWNDTGDHLQRLLRASVLDFACSMDDAASLNNASDLFNQWLQGNTNIQVLFLYFSIPSNLRLLVYRYGMQNSGNETSWNQMFRKYQETSLAQEKDKLLYGLASVNNITLLDRYLKYIYNTSLIKSQDVFTVLRYISYNTYGKTMAWDWIRLNWEYLVDRFTINDRNLGRIVTISQTFNTELQLWQMENFFEKYPNAGAGESPRSQSIEQVKNNIEWLKVNKEEIRTWLES

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue652

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KL380283
EMBL· GenBank· DDBJ
KFP86813.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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