A0A061JBK6 · A0A061JBK6_TRYRA

Function

function

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Biological Processchromatin organization
Biological ProcessDNA repair
Biological Processregulation of DNA-templated transcription

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein AF-9 homolog

Gene names

    • ORF names
      TRSC58_01637

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SC58
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma > Herpetosoma

Accessions

  • Primary accession
    A0A061JBK6

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region84-222Disordered
Compositional bias106-138Polar residues
Compositional bias154-170Polar residues
Compositional bias172-188Acidic residues
Compositional bias189-216Basic and acidic residues
Region396-435Disordered
Compositional bias397-424Basic and acidic residues

Sequence similarities

Belongs to the YAF9 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    677
  • Mass (Da)
    74,214
  • Last updated
    2014-09-03 v1
  • Checksum
    BB8A60A6C1AAFCA1
MTVFTRVFTIHFDGSVYEASADCRVTRTLRELLLATLPPPPLRRAATWVEGYACSFGGQRLSLAAATEVAPTTLYVTLAAHSGAGGKTAAGRRGGSLKRRRPSSPGKGESSATEGGNDGKENNSNSGSDSSSSGDSNDESGEDVFRSHRQPYWRPRAAQSNISKNNTNNSSNYEEEDEDGDDEEGDEEEKHDMYRSCGRSTAKWRDKTDSDGSNDDASSCDGRQQEAVLPIIVGGVVRLINIESRDRSHQWTVYIRGLFNETEYLAQCIESVRFILDPSFTPSERVVRTAPFELTEVGWGEFVVKMQVQLRHYPRPIRVMLSSSSFASTANCESEIKVASNFLASQPMVPLSGLTRGPILSPVVHVLSQHRYHSGTDVVSPPSTVYAVSGGSRRGVAKTEVKVEKEDSSSDTNSKFRKDNVRPSEVRSPGQPTLATLEMSPGIVTLSHLLRFSHRPRRAHCIPPLGRPYEPEEHVGYTIVQTPVVTEQYDEIVVPDPPAPILEVAEALPRVLRRRIATVKTARAMAQLPQQQQRLLSSGGAPFGVAAAFTENGVSCWEYILQEEPDDAVLAESYLESVGETVLSPASAQHSGIDVLVPPPCADTQRQEHEQPPPPPAFYGIESPVVVKLPRGRRKLAGAEIDLVALKTAKKGLLEAIEKMRRELVLRQAAQTYQHYK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias106-138Polar residues
Compositional bias154-170Polar residues
Compositional bias172-188Acidic residues
Compositional bias189-216Basic and acidic residues
Compositional bias397-424Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AUPL01001637
EMBL· GenBank· DDBJ
ESL10627.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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