Proteomes · Salmonella agona (strain SL483)

Description

Salmonella species belong to the group of Enterobactericiae. These bacteria were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The majority of the components of these bacteria are identical, and at the DNA level, they are between 95% and 99% identical. Many Salmonella enterica are involved in causing diseases of the intestine (enteric means pertaining to the intestine). The nontyphoidal Salmonella are the leading cause of bacterial food borne illness in humans, making these pathogens an immediate biomedical, public health, and biodefense concern. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria, which then leads to systemic spread. Salmonella agona (strain SL483) is a major cause of human foodborne illness in the United States and around the world. It is also a major pathogen of swine and other food animals. As with many serovars of high public health importance, genetic and immunological data are lacking. S. agona has been identified recently as a serovar capable of receiving the Salmonella genomic island 1 (SGI1) multidrug resistance gene cluster by horizontal gene spread.

Components

Component nameGenome accession(s)Protein count
ChromosomeCP0011384,541
Plasmid pSL483CP00113752

Publications

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