Keywords - Degradation of host peptidoglycans during virus entry (KW-1236)
- DefinitionVirion exolysin involved in breaking down host cell peptidoglycans (e.g. murein, pseudomurein) to reach the host cytoplasmic membrane during virus entry. Exolysins are usually part of the tail or the base plate of prokaryotic viruses. Exolysins can display various enzymatic activities such as lysozyme, transglycosylase, muramidase or even protease activity. Murein hydrolases for example are widespread in bacteriophages infecting Gram-positive or Gram-negative bacteria.
- Category
- Gene Ontology (GO)
- Ancestors
- GraphicalDegradation of host peptidoglycans during virus entry
Related UniProtKB entries
Browse all 845 entries- Tape measure protein pb2 precursor · Gene: D18-19 · Escherichia phage T5 (Enterobacteria phage T5) · 1219 amino acids · Evidence at protein level · Annotation score: 5/5#Antimicrobial #Bacteriolytic enzyme #Lyase #Viral long flexible tail ejection system #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Pore-mediated penetration of viral genome into host cell #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Primer terminal protein · Gene: 3 · Bacillus phage phi29 (Bacteriophage phi-29) · 266 amino acids · Evidence at protein level · Annotation score: 5/5
- Peptidoglycan transglycosylase gp16 · Gene: 16 · Escherichia phage T7 (Bacteriophage T7) · EC:4.2.2.n1 · 1318 amino acids · Evidence at protein level · Annotation score: 5/5#Antimicrobial #Bacteriolytic enzyme #Hydrolase #Lyase #Viral short tail ejection system #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Virus entry into host cell
- Pre-baseplate central spike protein Gp5 · Gene: 5 · Enterobacteria phage T4 (Bacteriophage T4) · 575 amino acids · Evidence at protein level · Annotation score: 5/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Transglycosylase · Gene: VII · Enterobacteria phage PRD1 (Bacteriophage PRD1) · EC:4.2.2.n1 · 265 amino acids · Evidence at protein level · Annotation score: 5/5
- Morphogenesis protein 1 · Gene: 13 · Bacillus phage phi29 (Bacteriophage phi-29) · 365 amino acids · Evidence at protein level · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Metalloprotease #Multifunctional enzyme #Protease #Viral short tail ejection system #Cell wall biogenesis/degradation #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Peptidoglycan hydrolase gp5 · Gene: P5 (P11) · Pseudomonas phage phi6 (Bacteriophage phi-6) · 220 amino acids · Evidence at protein level · Annotation score: 4/5
- Probable tape measure protein · Gene: yomI · Bacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta) · 2285 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Lyase #Viral long flexible tail ejection system #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- DNA terminal protein · Gene: 3 (E) · Bacillus phage Nf (Bacteriophage Nf) · 266 amino acids · Inferred from homology · Annotation score: 3/5
- Morphogenesis protein 1 · Gene: 13 · Bacillus phage PZA (Bacteriophage PZA) · 365 amino acids · Inferred from homology · Annotation score: 3/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Metalloprotease #Multifunctional enzyme #Protease #Cell wall biogenesis/degradation #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- DNA terminal protein · Gene: 3 · Bacillus phage B103 (Bacteriophage B103) · 266 amino acids · Inferred from homology · Annotation score: 3/5
- Peptidoglycan hydrolase gp36 · Gene: gp36 · Pseudomonas phage phiKMV · EC:3.2.1.17 · 898 amino acids · Evidence at protein level · Annotation score: 3/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Viral short tail ejection system #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Virus entry into host cell
- Peptidoglycan hydrolase gp4 · Gene: 4 · Salmonella phage P22 (Bacteriophage P22) · 166 amino acids · Evidence at protein level · Annotation score: 3/5
- Peptidoglycan hydrolase gp36 · Gene: 36 · Enterobacteria phage SP6 (Bacteriophage SP6) · 978 amino acids · Predicted · Annotation score: 3/5#Antimicrobial #Bacteriolytic enzyme #Viral short tail ejection system #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Virus entry into host cell
- DNA terminal protein · Gene: 3 · Bacillus phage PZA (Bacteriophage PZA) · 266 amino acids · Inferred from homology · Annotation score: 3/5
- Peptidoglycan hydrolase gp181 · Pseudomonas phage phiKZ · 2237 amino acids · Evidence at protein level · Annotation score: 3/5
- Peptidoglycan hydrolase gp27 · Gene: 27 · Acyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1) · 160 amino acids · Inferred from homology · Annotation score: 2/5
- DNA terminal protein · Gene: 3 (E) · Bacillus phage M2 (Bacteriophage M2) · 15 amino acids · Inferred from homology · Annotation score: 2/5
- Peptidoglycan hydrolase P7 · Gene: VII · Pseudoalteromonas phage PM2 (Bacteriophage PM2) · 34 amino acids · Evidence at protein level · Annotation score: 2/5
- Pre-baseplate central spike protein · Gene: PS2_161 · Serratia phage PS2 · 577 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Pre-baseplate central spike protein · Gene: phiP43_124 · Proteus phage phiP4-3 · 576 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Pre-baseplate central spike protein · Escherichia phage EcS1 · 575 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Peptidoglycan transglycosylase gp16 · Escherichia phage PhiV-1 · EC:4.2.2.n1 · 1315 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Hydrolase #Lyase #Viral short tail ejection system #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Virus entry into host cell
- Pre-baseplate central spike protein · Gene: 157 · Klebsiella phage vB_KpM-SoFaint · 589 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell
- Pre-baseplate central spike protein · Gene: POP12_059 · Pectobacterium phage POP12 · 589 amino acids · Inferred from homology · Annotation score: 4/5#Antimicrobial #Bacteriolytic enzyme #Glycosidase #Hydrolase #Degradation of host cell envelope components during virus entry #Degradation of host peptidoglycans during virus entry #Viral genome ejection through host cell envelope #Viral penetration into host cytoplasm #Viral release from host cell #Viral tail assembly #Virus entry into host cell