Keywords - Kinetochore (KW-0995)
- DefinitionThe kinetochore is a complex assembled at centromeric region of DNA, which provides the major attachment point for the spindle microtubules. In monocentric chromosomes, the kinetochores of point centromeres bind a single microtubule and the larger kinetochores of regional centromeres interact with a number of microtubules. In holocentric chromosomes, the kinetochores bind the diffuse centromere along the length of the chromosomes.
- Category
- Gene Ontology (GO)
- Ancestors
- GraphicalKinetochore
Related UniProtKB entries
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- Ras association domain-containing protein 2 · Gene: RASSF2 (CENP-34, KIAA0168) · Homo sapiens (Human) · 326 amino acids · Evidence at protein level · Annotation score: 5/5
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- Cell division cycle protein 20 homolog · Gene: CDC20 · Homo sapiens (Human) · 499 amino acids · Evidence at protein level · Annotation score: 5/5
- Centromere protein R · Gene: ITGB3BP (CENPR, NRIF3) · Homo sapiens (Human) · 177 amino acids · Evidence at protein level · Annotation score: 5/5
- Shugoshin 2 · Gene: SGO2 (SGOL2) · Homo sapiens (Human) · 1265 amino acids · Evidence at protein level · Annotation score: 5/5
- Shugoshin 1 · Gene: SGO1 (SGOL1) · Homo sapiens (Human) · 561 amino acids · Evidence at protein level · Annotation score: 5/5
- Polyamine-modulated factor 1 · Gene: PMF1 · Homo sapiens (Human) · 205 amino acids · Evidence at protein level · Annotation score: 5/5
- Kinesin-like protein KIF2B · Gene: KIF2B · Homo sapiens (Human) · 673 amino acids · Evidence at protein level · Annotation score: 5/5
- Kinetochore protein Spc24 · Gene: SPC24 (SPBC24) · Homo sapiens (Human) · 197 amino acids · Evidence at protein level · Annotation score: 5/5
- Nucleoporin Nup37 · Gene: NUP37 · Homo sapiens (Human) · 326 amino acids · Evidence at protein level · Annotation score: 5/5
- Nuclear pore complex protein Nup133 · Gene: NUP133 · Homo sapiens (Human) · 1156 amino acids · Evidence at protein level · Annotation score: 5/5
- Histone acetyltransferase KAT5 · Gene: KAT5 (HTATIP, TIP60) · Homo sapiens (Human) · EC:2.3.1.48 · 513 amino acids · Evidence at protein level · Annotation score: 5/5
- Kinetochore-associated protein NSL1 homolog · Gene: NSL1 (C1orf48) · Homo sapiens (Human) · 281 amino acids · Evidence at protein level · Annotation score: 5/5
- Inner centromere protein · Gene: INCENP · Homo sapiens (Human) · 918 amino acids · Evidence at protein level · Annotation score: 5/5
- F-box only protein 28 · Gene: FBXO28 (CENP-30, KIAA0483) · Homo sapiens (Human) · 368 amino acids · Evidence at protein level · Annotation score: 5/5
- Centromere/kinetochore protein zw10 homolog · Gene: ZW10 · Homo sapiens (Human) · 779 amino acids · Evidence at protein level · Annotation score: 5/5
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