Keywords - Insecticide resistance (KW-0978)
- DefinitionProtein that confers, on insect vectors and pests, the ability to withstand insecticide action. Insecticides are chemicals that selectively kill insects. Insecticide resistance usually occurs by two broad mechanisms. The first is where the insect may produce large amounts of enzymes, such as esterases which either break down the insecticide molecule or bind to it so tightly that it cannot function (a process known as sequestration). The second mechanism involves mutation of the insecticide target site, such as the acetylcholinesterase enzyme in the nervous system. This effectively blocks the action of the insecticide.
- Synonyms
- Category
- Gene Ontology (GO)
- Ancestors
- GraphicalInsecticide resistance
Related UniProtKB entries
Browse all 9 entries- Beta-1,3-galactosyltransferase bre-5 · Gene: bre-5 · Caenorhabditis elegans · EC:2.4.1.- · 322 amino acids · Evidence at protein level · Annotation score: 5/5
- GDP-mannose 4,6 dehydratase 1 · Gene: bre-1 (gmd-1) · Caenorhabditis elegans · EC:4.2.1.47 · 399 amino acids · Evidence at protein level · Annotation score: 5/5
- Beta-1,4-N-acetylgalactosaminyltransferase bre-4 · Gene: bre-4 · Caenorhabditis elegans · EC:2.4.1.- · 383 amino acids · Evidence at protein level · Annotation score: 5/5
- Beta-1,3-galactosyltransferase bre-2 · Gene: bre-2 · Caenorhabditis elegans · EC:2.4.1.- · 359 amino acids · Evidence at protein level · Annotation score: 4/5
- Beta-1,4-mannosyltransferase bre-3 · Gene: bre-3 · Caenorhabditis elegans · EC:2.4.1.- · 455 amino acids · Evidence at transcript level · Annotation score: 4/5
- Beta-1,4-N-acetylgalactosaminyltransferase bre-4 · Gene: bre-4 · Caenorhabditis briggsae · EC:2.4.1.- · 384 amino acids · Inferred from homology · Annotation score: 4/5
- GDP-mannose 4,6 dehydratase 1 · Gene: CBG21737 · Caenorhabditis briggsae · EC:4.2.1.47 · 377 amino acids · Inferred from homology · Annotation score: 3/5
- Beta-1,3-galactosyltransferase bre-2 · Gene: bre-2.1 (bre-2) · Caenorhabditis briggsae · EC:2.4.1.- · 365 amino acids · Inferred from homology · Annotation score: 3/5
- Beta-1,4-mannosyltransferase bre-3 · Gene: bre-3 · Caenorhabditis briggsae · EC:2.4.1.- · 455 amino acids · Inferred from homology · Annotation score: 2/5