Keywords - Glaucoma (KW-0955)
- DefinitionProtein which, if defective, causes glaucoma, a group of eye diseases characterized by pathological changes in the optic disk, progressive loss of optic nerve axons and visual field defects. Most of the patients with glaucoma have an increased intraocular pressure. The disease is painless and often diagnosed at a late stage, when visual field defects are severe. Glaucoma is one of the leading causes of blindness worldwide.
- Category
- Gene Ontology (GO)
- Ancestors
- GraphicalGlaucoma
Related UniProtKB entries
Browse all 15 entries- Calcium load-activated calcium channel · Gene: TMCO1 (TMCC4) · Homo sapiens (Human) · 239 amino acids · Evidence at protein level · Annotation score: 5/5
- Collagen alpha-1(XVIII) chain · Gene: COL18A1 · Homo sapiens (Human) · 1754 amino acids · Evidence at protein level · Annotation score: 5/5
- Ankyrin repeat and SOCS box protein 10 · Gene: ASB10 · Homo sapiens (Human) · 467 amino acids · Evidence at protein level · Annotation score: 5/5
- WD repeat-containing protein 36 · Gene: WDR36 · Homo sapiens (Human) · 951 amino acids · Evidence at protein level · Annotation score: 5/5
- Optineurin · Gene: OPTN (FIP2, GLC1E, HIP7, HYPL, NRP) · Homo sapiens (Human) · 577 amino acids · Evidence at protein level · Annotation score: 5/5
- X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 · Gene: RPGRIP1 · Homo sapiens (Human) · 1286 amino acids · Evidence at protein level · Annotation score: 5/5
- Angiopoietin-1 receptor · Gene: TEK (TIE2, VMCM, VMCM1) · Homo sapiens (Human) · EC:2.7.10.1 · 1124 amino acids · Evidence at protein level · Annotation score: 5/5
- EGF-containing fibulin-like extracellular matrix protein 1 · Gene: EFEMP1 (FBLN3, FBNL) · Homo sapiens (Human) · 493 amino acids · Evidence at protein level · Annotation score: 5/5
- Latent-transforming growth factor beta-binding protein 2 · Gene: LTBP2 (C14orf141, LTBP3) · Homo sapiens (Human) · 1821 amino acids · Evidence at protein level · Annotation score: 5/5
- G patch domain-containing protein 3 · Gene: GPATCH3 (GPATC3) · Homo sapiens (Human) · 525 amino acids · Evidence at protein level · Annotation score: 5/5
- Neurotrophin-4 · Gene: NTF4 (NTF5) · Homo sapiens (Human) · 210 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 1 · Gene: LOXL1 (LOXL) · Homo sapiens (Human) · EC:1.4.3.13 · 574 amino acids · Evidence at protein level · Annotation score: 5/5
- Cytochrome P450 1B1 · Gene: CYP1B1 · Homo sapiens (Human) · EC:1.14.14.1 · 543 amino acids · Evidence at protein level · Annotation score: 5/5
- Myocilin · Gene: MYOC (GLC1A, TIGR) · Homo sapiens (Human) · 504 amino acids · Evidence at protein level · Annotation score: 5/5
- Serine/threonine-protein kinase TBK1 · Gene: TBK1 (NAK) · Homo sapiens (Human) · EC:2.7.11.1 · 729 amino acids · Evidence at protein level · Annotation score: 5/5