Keywords - Vitamin D (KW-0848)
- DefinitionProtein which interacts with any form of the fat-soluble vitamin D or protein whose transcription is regulated by the biologically active form of vitamin D, i.e. 1,25-dihydroxy vitamin D3 (1,25 dihydroxycholecalciferol) also termed calcitriol. Active calcitriol is derived from ergosterol (produced in plants) and 7-dehydrocholesterol (produced in the skin). Ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3) are formed by UV irradiation of ergosterol and 7-dehydrocholesterol, respectively, and processed by the same enzymatic pathway in the body to D2-calcitriol and D3- calcitriol. Deficiency in vitamin D leads to the disease rickets, in children, and osteomalacia, in adults.
- Category
- Gene Ontology (GO)
- Ancestors
- GraphicalVitamin D
Related UniProtKB entries
Browse all 1,659 entries- Vitamin D-binding protein · Gene: GC · Homo sapiens (Human) · 474 amino acids · Evidence at protein level · Annotation score: 5/5
- Calbindin · Gene: CALB1 (CAB27) · Homo sapiens (Human) · 261 amino acids · Evidence at protein level · Annotation score: 5/5
- Klotho · Gene: KL · Homo sapiens (Human) · EC:3.2.1.31 · 1012 amino acids · Evidence at protein level · Annotation score: 5/5
- Iroquois-class homeodomain protein IRX-5 · Gene: IRX5 (IRX2A, IRXB2) · Homo sapiens (Human) · 483 amino acids · Evidence at protein level · Annotation score: 5/5
- Vitamin D-binding protein · Gene: Gc (Dbp) · Rattus norvegicus (Rat) · 476 amino acids · Evidence at protein level · Annotation score: 5/5
- Calbindin · Gene: Calb1 · Mus musculus (Mouse) · 261 amino acids · Evidence at protein level · Annotation score: 5/5
- Calbindin · Gene: Calb1 · Rattus norvegicus (Rat) · 261 amino acids · Evidence at protein level · Annotation score: 5/5
- Vitamin D-binding protein · Gene: Gc · Mus musculus (Mouse) · 476 amino acids · Evidence at protein level · Annotation score: 5/5
- B box and SPRY domain-containing protein · Gene: Bspry · Mus musculus (Mouse) · 473 amino acids · Evidence at protein level · Annotation score: 5/5
- Calbindin · Gene: CALB1 · Gallus gallus (Chicken) · 262 amino acids · Evidence at protein level · Annotation score: 5/5
- Protein S100-G · Gene: S100G (CABP9K, CALB3, S100D) · Homo sapiens (Human) · 79 amino acids · Evidence at protein level · Annotation score: 4/5
- Protein S100-G · Gene: S100g (Calb3, S100d) · Rattus norvegicus (Rat) · 79 amino acids · Evidence at protein level · Annotation score: 4/5
- Calbindin · Gene: CALB1 · Bos taurus (Bovine) · 261 amino acids · Evidence at protein level · Annotation score: 4/5
- Protein S100-G · Gene: S100G (CALB3, S100D) · Sus scrofa (Pig) · 79 amino acids · Evidence at protein level · Annotation score: 4/5
- Protein S100-G · Gene: S100G (CALB3, S100D) · Bos taurus (Bovine) · 79 amino acids · Evidence at protein level · Annotation score: 3/5
- Protein S100-G · Gene: S100g (Calb3, S100d) · Mus musculus (Mouse) · 79 amino acids · Evidence at protein level · Annotation score: 3/5
- Vitamin D-binding protein · Gene: GC · Bos taurus (Bovine) · 474 amino acids · Evidence at transcript level · Annotation score: 3/5
- Calbindin · Gene: CALB1 · Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) · 261 amino acids · Evidence at transcript level · Annotation score: 3/5
- Protein S100-G · Gene: S100G · Equus caballus (Horse) · 79 amino acids · Inferred from homology · Annotation score: 3/5
- Vitamin D-binding protein · Gene: GC (DBP) · Oryctolagus cuniculus (Rabbit) · 476 amino acids · Evidence at transcript level · Annotation score: 3/5
- Calbindin · Gene: CALB1 · Pan paniscus (Pygmy chimpanzee) (Bonobo) · 261 amino acids · Inferred from homology · Annotation score: 4/5
- Calbindin · Gene: CALB1 · Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) · 261 amino acids · Inferred from homology · Annotation score: 4/5
- Calbindin · Gene: CALB1 · Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby) · 261 amino acids · Inferred from homology · Annotation score: 4/5
- Calbindin · Gene: CALB1 · Pan troglodytes (Chimpanzee) · 261 amino acids · Inferred from homology · Annotation score: 4/5
- Calbindin · Gene: CALB1 · Anas platyrhynchos platyrhynchos (Northern mallard) · 262 amino acids · Inferred from homology · Annotation score: 4/5