Keywords - TPQ (KW-0801)
- DefinitionProtein which is posttranslationally modified on a tyrosine residue to form TPQ. This modification of a strictly conserved active-site tyrosine residue proceeds via the hydroxylation of tyrosine to Topa (Trihydroxyphenylalanine) and then to TPQ (Topaquinone). It is a self- processing pathway requiring only the protein, copper and molecular oxygen. TPQ is the redox cofactor of most copper-containing amine oxidases.
- Synonyms
- Category
- Gene Ontology (GO)
- Ancestors
- GraphicalTPQ
Related UniProtKB entries
Browse all 24,621 entries- Amine oxidase [copper-containing] 2 · Gene: AOC2 · Homo sapiens (Human) · EC:1.4.3.21 · 756 amino acids · Evidence at protein level · Annotation score: 5/5
- Amine oxidase [copper-containing] 3 · Gene: AOC3 (VAP1) · Homo sapiens (Human) · EC:1.4.3.21 · 763 amino acids · Evidence at protein level · Annotation score: 5/5
- Protein-lysine 6-oxidase · Gene: LOX · Homo sapiens (Human) · EC:1.4.3.13 · 417 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 3 · Gene: LOXL3 (LOXL) · Homo sapiens (Human) · EC:1.4.3.-, EC:1.4.3.13 · 753 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 1 · Gene: LOXL1 (LOXL) · Homo sapiens (Human) · EC:1.4.3.13 · 574 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 2 · Gene: LOXL2 · Homo sapiens (Human) · EC:1.4.3.13 · 774 amino acids · Evidence at protein level · Annotation score: 5/5
- Diamine oxidase [copper-containing] · Gene: AOC1 (ABP, ABP1, DAO) · Homo sapiens (Human) · EC:1.4.3.22 · 751 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 4 · Gene: LOXL4 (LOXC) · Homo sapiens (Human) · EC:1.4.3.13 · 756 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 2A · Gene: loxl2a · Danio rerio (Zebrafish) (Brachydanio rerio) · EC:1.4.3.13 · 737 amino acids · Evidence at transcript level · Annotation score: 5/5
- Diamine oxidase [copper-containing] · Gene: Aoc1 (Abp1) · Mus musculus (Mouse) · EC:1.4.3.22 · 751 amino acids · Evidence at transcript level · Annotation score: 5/5
- Amine oxidase [copper-containing] 3 · Gene: AOC3 · Bos taurus (Bovine) · EC:1.4.3.21 · 763 amino acids · Evidence at transcript level · Annotation score: 5/5
- Lysyl oxidase homolog 3A · Gene: loxl3a · Danio rerio (Zebrafish) (Brachydanio rerio) · EC:1.4.3.-, EC:1.4.3.13 · 739 amino acids · Evidence at transcript level · Annotation score: 5/5
- Amine oxidase [copper-containing] alpha 2, peroxisomal · Gene: CuAOalpha2 (CuAO8) · Arabidopsis thaliana (Mouse-ear cress) · EC:1.4.3.21 · 677 amino acids · Evidence at protein level · Annotation score: 5/5
- Amine oxidase [copper-containing] alpha 3, peroxisomal · Gene: CuAOalpha3 (CuAO2) · Arabidopsis thaliana (Mouse-ear cress) · EC:1.4.3.21 · 681 amino acids · Evidence at protein level · Annotation score: 5/5
- Protein-lysine 6-oxidase · Gene: Lox (Rrg) · Mus musculus (Mouse) · EC:1.4.3.13 · 411 amino acids · Evidence at protein level · Annotation score: 5/5
- Primary amine oxidase 1 · Gene: AO1 · Arabidopsis thaliana (Mouse-ear cress) · EC:1.4.3.21 · 650 amino acids · Evidence at protein level · Annotation score: 5/5
- Primary amine oxidase · Gene: tynA (maoA) · Escherichia coli (strain K12) · EC:1.4.3.21 · 757 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 2 · Gene: Loxl2 · Mus musculus (Mouse) · EC:1.4.3.13 · 776 amino acids · Evidence at protein level · Annotation score: 5/5
- Amine oxidase [copper-containing] gamma 1 · Gene: CuAOgamma1 (CuAO1) · Arabidopsis thaliana (Mouse-ear cress) · EC:1.4.3.21 · 712 amino acids · Evidence at protein level · Annotation score: 5/5
- Amine oxidase [copper-containing] zeta, peroxisomal · Gene: CuAOzeta (CuAO1, CuAO3) · Arabidopsis thaliana (Mouse-ear cress) · EC:1.4.3.21 · 776 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 2 · Gene: LOXL2 · Bos taurus (Bovine) · EC:1.4.3.13 · 774 amino acids · Evidence at transcript level · Annotation score: 5/5
- Protein-lysine 6-oxidase · Gene: Lox · Rattus norvegicus (Rat) · EC:1.4.3.13 · 411 amino acids · Evidence at protein level · Annotation score: 5/5
- Diamine oxidase [copper-containing] · Gene: Aoc1 (Abp1) · Rattus norvegicus (Rat) · EC:1.4.3.22 · 746 amino acids · Evidence at transcript level · Annotation score: 5/5
- Primary amine oxidase, liver isozyme · Bos taurus (Bovine) · EC:1.4.3.21 · 762 amino acids · Evidence at protein level · Annotation score: 5/5
- Lysyl oxidase homolog 1 · Gene: LOXL1 · Bos taurus (Bovine) · EC:1.4.3.13 · 591 amino acids · Evidence at protein level · Annotation score: 5/5