Keywords - Nuclease (KW-0540)
- DefinitionEnzyme that degrades nucleic acids into shorter oligonucleotides or single nucleotide subunits by hydrolyzing sugar-phosphate bonds in the nucleic acid backbone.
- Category
- Gene Ontology (GO)
- Descendants
- Ancestors
- Graphical
Related UniProtKB entries
Browse all 2,600,887 entries- Probable crossover junction endonuclease EME2 · Gene: EME2 · Homo sapiens (Human) · EC:3.1.22.- · 379 amino acids · Evidence at protein level · Annotation score: 5/5
- Deoxyribonuclease-2-alpha · Gene: DNASE2 (DNASE2A, DNL2) · Homo sapiens (Human) · EC:3.1.22.1 · 360 amino acids · Evidence at protein level · Annotation score: 5/5
- Phospholipid scramblase 1 · Gene: PLSCR1 · Homo sapiens (Human) · 318 amino acids · Evidence at protein level · Annotation score: 5/5
- Ribonuclease H1 · Gene: RNASEH1 (RNH1) · Homo sapiens (Human) · EC:3.1.26.4 · 286 amino acids · Evidence at protein level · Annotation score: 5/5
- DNA fragmentation factor subunit beta · Gene: DFFB (CAD, DFF2, DFF40) · Homo sapiens (Human) · EC:3.-.-.- · 338 amino acids · Evidence at protein level · Annotation score: 5/5
- Decapping and exoribonuclease protein · Gene: DXO (DOM3L, DOM3Z, NG6) · Homo sapiens (Human) · EC:3.6.1.- · 396 amino acids · Evidence at protein level · Annotation score: 5/5
- Ribonuclease pancreatic · Gene: RNASE1 (RIB1, RNS1) · Homo sapiens (Human) · EC:4.6.1.18 · 156 amino acids · Evidence at protein level · Annotation score: 5/5
- Non-secretory ribonuclease · Gene: RNASE2 (EDN, RNS2) · Homo sapiens (Human) · EC:4.6.1.18 · 161 amino acids · Evidence at protein level · Annotation score: 5/5
- Uridylate-specific endoribonuclease · Gene: ENDOU · Homo sapiens (Human) · EC:4.6.1.- · 410 amino acids · Evidence at protein level · Annotation score: 5/5
- DNA repair nuclease/redox regulator APEX1 · Gene: APEX1 (APE, APE1, APEX, APX, HAP1, REF1) · Homo sapiens (Human) · EC:3.1.11.2, EC:3.1.21.- · 318 amino acids · Evidence at protein level · Annotation score: 5/5
- DNA polymerase delta catalytic subunit · Gene: POLD1 (POLD) · Homo sapiens (Human) · EC:2.7.7.7 · 1107 amino acids · Evidence at protein level · Annotation score: 5/5
- DNA replication ATP-dependent helicase/nuclease DNA2 · Gene: DNA2 (DNA2L, KIAA0083) · Homo sapiens (Human) · 1060 amino acids · Evidence at protein level · Annotation score: 5/5
- 2-5A-dependent ribonuclease · Gene: RNASEL (RNS4) · Homo sapiens (Human) · EC:3.1.26.- · 741 amino acids · Evidence at protein level · Annotation score: 5/5
- Schlafen family member 13 · Gene: SLFN13 · Homo sapiens (Human) · EC:3.1.-.- · 897 amino acids · Evidence at protein level · Annotation score: 5/5
- PiggyBac transposable element-derived protein 5 · Gene: PGBD5 · Homo sapiens (Human) · EC:3.1.-.- · 524 amino acids · Evidence at protein level · Annotation score: 5/5
- Ankyrin repeat and LEM domain-containing protein 1 · Gene: ANKLE1 (ANKRD41, LEM3) · Homo sapiens (Human) · EC:3.1.-.- · 615 amino acids · Evidence at protein level · Annotation score: 5/5
- Polyribonucleotide nucleotidyltransferase 1, mitochondrial · Gene: PNPT1 (PNPASE) · Homo sapiens (Human) · EC:2.7.7.8 · 783 amino acids · Evidence at protein level · Annotation score: 5/5
- Putative nuclease HARBI1 · Gene: HARBI1 (C11orf77) · Homo sapiens (Human) · EC:3.1.-.- · 349 amino acids · Evidence at protein level · Annotation score: 5/5
- Mitochondrial genome maintenance exonuclease 1 · Gene: MGME1 (C20orf72, DDK1) · Homo sapiens (Human) · EC:3.1.-.- · 344 amino acids · Evidence at protein level · Annotation score: 5/5
- RNA exonuclease 4 · Gene: REXO4 (PMC2, XPMC2H) · Homo sapiens (Human) · EC:3.1.-.- · 422 amino acids · Evidence at protein level · Annotation score: 5/5
- Ribonuclease 7 · Gene: RNASE7 · Homo sapiens (Human) · EC:3.1.27.- · 156 amino acids · Evidence at protein level · Annotation score: 5/5
- Ribonuclease 3 · Gene: DROSHA (RN3, RNASE3L, RNASEN) · Homo sapiens (Human) · EC:3.1.26.3 · 1374 amino acids · Evidence at protein level · Annotation score: 5/5
- RNA-binding protein NOB1 · Gene: NOB1 (ART4, NOB1P, PSMD8BP1) · Homo sapiens (Human) · EC:3.1.-.- · 412 amino acids · Evidence at protein level · Annotation score: 5/5
- Nuclease EXOG, mitochondrial · Gene: EXOG (ENDOGL1, ENDOGL2, ENGL) · Homo sapiens (Human) · EC:3.1.30.- · 368 amino acids · Evidence at protein level · Annotation score: 5/5
- Fanconi-associated nuclease 1 · Gene: FAN1 (KIAA1018, MTMR15) · Homo sapiens (Human) · EC:3.1.21.-, EC:3.1.4.1 · 1017 amino acids · Evidence at protein level · Annotation score: 5/5