Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)P9WHG9[398 - 459]
Description
Feature keyDomain
Feature identifier
        10         20         30         40         50
MTAQRSTTNP VLEPLVAVHR EIYPKADLSI LQRAYEVADQ RHASQLRQSG
60 70 80 90 100
DPYITHPLAV ANILAELGMD TTTLVAALLH DTVEDTGYTL EALTEEFGEE
110 120 130 140 150
VGHLVDGVTK LDRVVLGSAA EGETIRKMIT AMARDPRVLV IKVADRLHNM
160 170 180 190 200
RTMRFLPPEK QARKARETLE VIAPLAHRLG MASVKWELED LSFAILHPKK
210 220 230 240 250
YEEIVRLVAG RAPSRDTYLA KVRAEIVNTL TASKIKATVE GRPKHYWSIY
260 270 280 290 300
QKMIVKGRDF DDIHDLVGVR ILCDEIRDCY AAVGVVHSLW QPMAGRFKDY
310 320 330 340 350
IAQPRYGVYQ SLHTTVVGPE GKPLEVQIRT RDMHRTAEYG IAAHWRYKEA
360 370 380 390 400
KGRNGVLHPH AAAEIDDMAW MRQLLDWQRE AADPGEFLES LRYDLAVQEI
410 420 430 440 450
FVFTPKGDVI TLPTGSTPVD FAYAVHTEVG HRCIGARVNG RLVALERKLE
460 470 480 490 500
NGEVVEVFTS KAPNAGPSRD WQQFVVSPRA KTKIRQWFAK ERREEALETG
510 520 530 540 550
KDAMAREVRR GGLPLQRLVN GESMAAVARE LHYADVSALY TAIGEGHVSA
560 570 580 590 600
KHVVQRLLAE LGGIDQAEEE LAERSTPATM PRRPRSTDDV GVSVPGAPGV
610 620 630 640 650
LTKLAKCCTP VPGDVIMGFV TRGGGVSVHR TDCTNAASLQ QQAERIIEVL
660 670 680 690 700
WAPSPSSVFL VAIQVEALDR HRLLSDVTRA LADEKVNILS ASVTTSGDRV
710 720 730
AISRFTFEMG DPKHLGHLLN AVRNVEGVYD VYRVTSAA
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again