W0DBY5 · W0DBY5_9AQUI

  • Protein
    Delta-aminolevulinic acid dehydratase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.

Features

Showing features for binding site, active site.

132750100150200250300
TypeIDPosition(s)Description
Binding site120Zn2+ (UniProtKB | ChEBI); catalytic
Binding site122Zn2+ (UniProtKB | ChEBI); catalytic
Binding site130Zn2+ (UniProtKB | ChEBI); catalytic
Active site195Schiff-base intermediate with substrate
Binding site2055-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site2175-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site233Mg2+ (UniProtKB | ChEBI)
Active site248Schiff-base intermediate with substrate
Binding site2745-aminolevulinate 2 (UniProtKB | ChEBI)
Binding site3135-aminolevulinate 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionporphobilinogen synthase activity
Molecular Functionzinc ion binding
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Delta-aminolevulinic acid dehydratase
  • EC number

Gene names

    • ORF names
      THERU_02570

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 23557
  • Taxonomic lineage
    Bacteria > Aquificota > Aquificia > Aquificales > Aquificaceae > Thermocrinis

Accessions

  • Primary accession
    W0DBY5

Proteomes

Subcellular Location

Interaction

Subunit

Homooctamer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the ALAD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    36,544
  • Last updated
    2014-03-19 v1
  • Checksum
    458B5EA0163EBA96
MEFPKLRPRRLRLSENIRRLVRETRLTLDDLIYPIFVRYGENIVEEVPSMPGVYRYSVDRVVDAVKEVRDLGIPAIILFGIPEHKDEIGSDTWSEQGIIQRALRRIKKEVPEMYVITDVCFCEYTTHGHCGVLKGHTVDNDLTLENLKKQVISHAENGADMVAPSGMMDGMVQAIRSALDSAGYTHIPIMAYSAKFASAFYGPFRDAAESAPAFGDRRSYQMDPANAREALKEVLLDVQEGADIVMVKPALAYLDIIAKVKEATLIPVCAYNVSGEYAMIKAAGRLGWIDEEKVMIETLISIKRAGADMIITYFAKDVAKLINKGII

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP007028
EMBL· GenBank· DDBJ
AHE95746.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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