V9IDN8 · V9IDN8_APICE
- ProteinDelta-1-pyrroline-5-carboxylate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids783 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- L-glutamate + ATP = L-glutamyl 5-phosphate + ADP
Pathway
Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.
Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | glutamate 5-kinase activity | |
Molecular Function | glutamate-5-semialdehyde dehydrogenase activity | |
Biological Process | L-proline biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDelta-1-pyrroline-5-carboxylate synthase
Including 2 domains:
- Recommended nameGlutamate 5-kinase
- EC number
- Short namesGK
- Alternative names
- Recommended nameGamma-glutamyl phosphate reductase
- EC number
- Short namesGPR
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Apoidea > Anthophila > Apidae > Apis
Accessions
- Primary accessionV9IDN8
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 19-47 | Disordered | |||
Compositional bias | 34-47 | Basic and acidic residues | |||
Domain | 65-324 | Aspartate/glutamate/uridylate kinase | |||
Domain | 353-650 | Aldehyde dehydrogenase | |||
Sequence similarities
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
In the N-terminal section; belongs to the glutamate 5-kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length783
- Mass (Da)84,883
- Last updated2014-03-19 v1
- MD5 Checksum6F8F76EE6A3F86F2A0967B531D44051A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 34-47 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JR039595 EMBL· GenBank· DDBJ | AEY58772.1 EMBL· GenBank· DDBJ | mRNA |