V9IDN8 · V9IDN8_APICE

Function

Catalytic activity

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.
Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular FunctionATP binding
Molecular Functionglutamate 5-kinase activity
Molecular Functionglutamate-5-semialdehyde dehydrogenase activity
Biological ProcessL-proline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Delta-1-pyrroline-5-carboxylate synthase

Including 2 domains:

  • Recommended name
    Glutamate 5-kinase
  • EC number
  • Short names
    GK
  • Alternative names
    • Gamma-glutamyl kinase
  • Recommended name
    Gamma-glutamyl phosphate reductase
  • EC number
  • Short names
    GPR
  • Alternative names
    • Glutamate-5-semialdehyde dehydrogenase
    • Glutamyl-gamma-semialdehyde dehydrogenase

Gene names

    • ORF names
      ACCB01381.1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Apoidea > Anthophila > Apidae > Apis

Accessions

  • Primary accession
    V9IDN8

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region19-47Disordered
Compositional bias34-47Basic and acidic residues
Domain65-324Aspartate/glutamate/uridylate kinase
Domain353-650Aldehyde dehydrogenase

Sequence similarities

In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
In the N-terminal section; belongs to the glutamate 5-kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    783
  • Mass (Da)
    84,883
  • Last updated
    2014-03-19 v1
  • MD5 Checksum
    6F8F76EE6A3F86F2A0967B531D44051A
MYARLLLLRSSKLGCFPRRLASSSSGPRVPEQASRVDSRRELQTTEGPRKATMFNDRSQLNYTRRLVVKLGSAVITREDEHGLALGRLASIVEQVAECQNGGRECIMVTSGAVAFGKQKLAQELLMSLSMRETLSPGGHMRKRSGTPLEPRAAAAVGQSGLMSLYDAMFAQYGVKLAQVLVTKPDFYNEETRNNLFSTLSELLSLNIVPIINTNDAVSPPPHVDEEVAGSGGRRGISIKDNDSLAAMLAAEIQADLLILMSDVDGIYNLPPWQDGAKMLHTFSMDLRDTIKFGQKSKVGTGGMDAKVNAALWALDRGVSVVICNGTQEKAIKNILSGRKIGTFFTQTTEISTPVEVVAEEARTGSRALQALRPEERASCINALADLLESRQKEILEANRKDLEAAEKTGLAKALLSRLSLTPAKLKSLSSGLRQIANDSLTNVGRVLRRTKLAEGLELRQITVPIGVLLVIFESRPDSLPQVAALAMSSANGLLLKGGKEATNSNKYLMELVKEALSPVGAANAISLISTREDVGDLLSMGKHIDLVIPRGSSDLVRSIQEQSKHIPVLGHAEGICHVFVDRDADLVKALKIIRDSKCDYPAACNAMETLLIHESHMKSNFFNDVCSMLQNEGVKVNSGPKLRKQLTFGPPPAKSMKTEYGALECAIEVVSDIEDAINHIHKYGSGHTDCIVTENKERATYFQREVDSACVFHNASTRFSDGYRFGLGAEVGISTARIHARGPVGVDGLLTTKWVLQGNGHAAADFGEGGEVWLHQSLPLNEI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias34-47Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JR039595
EMBL· GenBank· DDBJ
AEY58772.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice.
Help