U3C0T9 · U3C0T9_CALJA

Function

Features

Showing features for dna binding.

130320406080100120140160180200220240260280300
TypeIDPosition(s)Description
DNA binding172-231Homeobox

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnuclear periphery
Cellular Componentnucleoplasm
Cellular Componenttranscription regulator complex
Molecular Functioncis-regulatory region sequence-specific DNA binding
Molecular FunctionDNA-binding transcription activator activity, RNA polymerase II-specific
Molecular FunctionDNA-binding transcription repressor activity, RNA polymerase II-specific
Molecular Functionp53 binding
Molecular FunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding
Biological Processactivation of meiosis
Biological Processanterior/posterior pattern specification
Biological ProcessBMP signaling pathway
Biological Processbone morphogenesis
Biological Processcartilage morphogenesis
Biological Processcell morphogenesis
Biological Processcell surface receptor signaling pathway involved in heart development
Biological Processembryonic forelimb morphogenesis
Biological Processembryonic hindlimb morphogenesis
Biological Processembryonic nail plate morphogenesis
Biological Processepithelial to mesenchymal transition involved in endocardial cushion formation
Biological Processface morphogenesis
Biological Processforebrain development
Biological Processin utero embryonic development
Biological Processinner ear development
Biological Processmammary gland epithelium development
Biological Processmesenchymal cell apoptotic process
Biological Processmesenchymal cell proliferation
Biological Processmidbrain development
Biological Processmiddle ear morphogenesis
Biological Processmuscle organ development
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of cell growth
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of gene expression
Biological Processnegative regulation of odontoblast differentiation
Biological Processnegative regulation of striated muscle cell differentiation
Biological Processnose development
Biological Processodontogenesis of dentin-containing tooth
Biological Processpositive regulation of BMP signaling pathway
Biological Processpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
Biological Processpositive regulation of mesenchymal cell apoptotic process
Biological Processpositive regulation of odontogenesis
Biological Processprotein localization to nucleus
Biological Processprotein stabilization
Biological Processroof of mouth development
Biological Processsignal transduction involved in regulation of gene expression
Biological Processstem cell differentiation
Biological Processtranscription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Homeobox protein MSX-1
  • Alternative names
    • Msh homeobox 1-like protein

Gene names

    • Name
      MSX1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Platyrrhini > Cebidae > Callitrichinae > Callithrix > Callithrix

Accessions

  • Primary accession
    U3C0T9

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Keywords

Interaction

Subunit

Interacts with CREBBP/CBP, TBP and SP1; interaction with these transcription activators may inhibit autoinactivation. Interacts (via C-terminus) with PIAS1 (via N-terminus); the interaction is required for the localization of both proteins to the nuclear periphery and specific binding of MSX1 to the core enhancer region in target gene promoters. Interacts with H1-5.

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region18-56Disordered
Region69-116Disordered
Compositional bias133-142Basic and acidic residues
Region133-163Disordered
Domain170-230Homeobox

Sequence similarities

Belongs to the Msh homeobox family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    303
  • Mass (Da)
    31,516
  • Last updated
    2013-11-13 v1
  • MD5 Checksum
    DD4A6E54DA0963FECC55209D965501E1
MAPSADMTSLPLGVKVEDSAFGKPAGGGSGQAPGAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESSLAASESAQAAGGLAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias133-142Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GAMT01007305
EMBL· GenBank· DDBJ
JAB04556.1
EMBL· GenBank· DDBJ
mRNA
GAMS01004163
EMBL· GenBank· DDBJ
JAB18973.1
EMBL· GenBank· DDBJ
mRNA
GAMR01009123
EMBL· GenBank· DDBJ
JAB24809.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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